Evidence map›Paper›PMID 35041442›Full record

Trial reportExperimental and clinical psychopharmacology2022

Future thinking to decrease real-world drinking in alcohol use disorder: Repairing reinforcer pathology in a randomized proof-of-concept trial.

Liqa N Athamneh, Jeremiah Brown, Jeffrey S Stein, Kirstin M Gatchalian, Stephen M LaConte, Warren K Bickel

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Experimental and clinical psychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Imagining the future can shape the present: A systematic review of the impact of episodic future thinking on substance use outcomes.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liqa N AthamnehAddiction Recovery Research Center.
Jeremiah BrownAddiction Recovery Research Center.ORCID 0000-0001-9044-8586
Jeffrey S SteinAddiction Recovery Research Center.ORCID 0000-0001-5251-3447
Kirstin M GatchalianAddiction Recovery Research Center.
Stephen M LaConteDepartment of Biomedical Engineering and Mechanics.
Warren K BickelAddiction Recovery Research Center.

Funding

Testing Reinforcer Pathology: Mechanisms and Interventions to Change Alcohol ValuationR01AA027381 · NIAAA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LACONTE, STEPHEN M · 2019 to 2023
$3.5M
The Repair of Self Control in Alcohol Dependence: Working Memory & Real Time fMRIR01AA021529 · NIAAA · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BICKEL, WARREN K, LACONTE, STEPHEN M · 2013 to 2017
$2.8M
NIAAA NIH HHS R01 AA021529NIAAA NIH HHS R01 AA027381NIH HHSVirginia Tech Fralin Biomedical Research Institute at VTC
6 · The paper itself

Abstract

Reinforcer Pathology theory proposes that expanding the temporal window of reinforcement (i.e., reducing delay discounting) using episodic future thinking (EFT) would decrease alcohol consumption. However, evidence of effectiveness in real-world settings is lacking. Using a randomized proof-of-concept field trial, the current study examined the effect of expanding the temporal window of reinforcement, using remotely delivered EFT, on decreasing real-world alcohol consumption among individuals with alcohol use disorder (AUD). Fifty-two individuals (9 females) aged 18-65 years who met the DSM-5 criteria for moderate or severe AUD and aimed to drink in moderation or abstain from drinking completed the study and were included in analysis. EFT significantly (p = .031) reduced alcohol consumption (mean change of consumption pre-post intervention = -2.18 drinks/day) compared to control episodic recent thinking (ERT; mean change of -0.52 drinks/day). Changes in discounting rates pre-post intervention significantly predicted changes in alcohol consumption (coef. = .424, 95% CI [.043-.813], p = .030) even after controlling for age, gender, race, income, education, marital status, and family history of addiction. Overall satisfaction across groups was rated as 3.92 on a 1 to 5-point scale, suggesting that the current remote approach is feasible and acceptable. The current findings were congruent with the theory, Reinforcer Pathology, that EFT expands the temporal window and decreases alcohol consumption, and the remote approach was considered feasible and acceptable. We believe the present study contributes new knowledge with tangible benefits for scientifically understanding and better defining novel interventions that may be clinically deployed to improve treatment outcomes. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Indexed as

AlcoholismBehavior, AddictiveDelay DiscountingAlcohol DrinkingFemaleHumansThinking

Identifiers

PMID35041442
PMCPMC9450688

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.