Evidence map›Paper›PMID 35041198›Full record

ReviewAmerican journal of clinical dermatology2022

New Developments in Topical Acne Therapy.

Lara Drake, Sophia Reyes-Hadsall, John S Barbieri, Arash Mostaghimi

Abstract readReview
PubMed Publisher
In one paragraph

Review in American journal of clinical dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Selective Modulation ofClinical, cosmetic and investigational dermatology · 2026
    Review
  3. Analysis of Reddit Reveals Clascoterone Questions Among People with Acne.The Journal of clinical and aesthetic dermatology · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Targeting Inflammation in Acne: Current Treatments and Future Prospects.American journal of clinical dermatology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lara Drake *Department of Dermatology, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0003-3107-6246
Sophia Reyes-Hadsall *Department of Dermatology, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0002-1580-8008
John S BarbieriDepartment of Dermatology, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA, 02115, USA.ORCID http://orcid.org/0000-0002-5467-4102
Arash MostaghimiDepartment of Dermatology, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA, 02115, USA. amostaghimi@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-6084-5617
Brigham and Women's Hospital · USTufts University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne vulgaris is a common chronic inflammatory disease with a multifactorial pathogenesis. Although myriad acne treatments are available, current options may not be sufficient because of a lack of efficacy, limited tolerability, or burden of cost to patients. In this review, we highlight recently approved topical acne treatments, as well as those currently in clinical trials. Novel formulations of tretinoin, tazarotene, and minocycline provide modifications of and improvements to existing products. Trifarotene, a novel fourth-generation retinoid, has demonstrated improved tolerability compared with existing topical retinoids. Clascoterone is a novel first-in-class antiandrogen that topically addresses the hormonal etiology of acne. The late-phase clinical trials pipeline consists of agents with bactericidal and anti-sebum mechanisms. Although it is evident that acne treatments continue to evolve, it is important to recognize the need for further comparative studies among new and existing agents to define optimal treatment algorithms that address not only safety and efficacy but also cost-effective care.

Indexed as

Acne VulgarisDermatologic AgentsHumansMinocyclineRetinoidsTreatment OutcomeTretinoinDermatologic AgentsMinocyclineRetinoidsTretinoin

Identifiers

PMID35041198
OpenAlexW4205132940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.