ArticleBrain imaging and behavior2022
Superior frontal gyrus and middle temporal gyrus connectivity mediates the relationship between neuroticism and thought suppression.
Article in Brain imaging and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- The clinical relevance of healthy neurodevelopmental connectivity in childhood and adolescence: a meta-analysis of resting-state fMRI.Frontiers in neuroscience · 2025Pooled it
- A systematic review and coordinate-based meta-analysis of fMRI studies on acupuncture at LR 3.Frontiers in neuroscience · 2024Pooled it
- Gray matter volume alterations in early-adulthood major depressive disorder patients with non-suicidal self-injury and suicide attempts.BMC psychiatry · 2026Article
- Altered cortical neuronal activity in functional esophageal disorders and its associations with chronic insomnia and peripheral inflammation: a resting-state fMRI study.Frontiers in molecular neuroscience · 2026Article
- Developing brain asymmetry shapes cognitive and psychiatric outcomes in adolescence.Nature communications · 2025Article
- Abnormal Gyrus Rectus Asymmetry in Alzheimer's Disease: An MRI-Based Parcellation Method.Brain sciences · 2025Article
- Resting state connectivity patterns associated with trait anxiety in adolescence.Scientific reports · 2025Article
- The Specificity of Metacognition Questionnaire-30 Subdimensions: Findings From Connectome-Based Predictive Modeling.Depression and anxiety · 2025Article
- Arterial spin labeling reveals disordered cerebral perfusion and cerebral blood flow-based functional connectivity in primary open-angle glaucoma.Brain imaging and behavior · 2024Article
- Alterations in brain morphology and functional connectivity mediate cognitive decline in carotid atherosclerotic stenosis.Frontiers in aging neuroscience · 2024Article
- Changes of regional brain activity following Tuina therapy for patients with painful cervical spondylosis: a resting-state fMRI study.Frontiers in neurology · 2024Article
- Neurological activation during verbal fluency task and resting-state functional connectivity abnormalities in obsessive-compulsive disorder: a functional near-infrared spectroscopy study.Frontiers in psychiatry · 2024Article
- Intrusive thinking: Circuit and synaptic mechanisms of a transdiagnostic psychiatric symptom.Neuroscience and biobehavioral reviews · 2023Review
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Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Thought suppression, which is defined as an effort "not to think about" a particular thought, is essential to maintain good mental health. Despite previous functional imaging studies on thought suppression and related functional activity, the neural basis of thought suppression in individual difference is still unclear. Many studies have focused on the relationship between neuroticism and thought suppression; however, the neural basis of this relationship is not well known. Thus, in the present study, we investigated the neural basis of thought suppression and further explored the neural mechanisms underlying the relationship between neuroticism and thought suppression. The first step was to use voxel-based morphometry (VBM) to investigate the neuroanatomical basis of thought suppression in healthy subjects. We found a significant positive correlation between thought suppression and the gray matter volume (GMV) of the right superior frontal gyrus (SFG). The second step was to use resting-state functional connectivity (rsFC) to investigate the neural functional basis of thought suppression. The results showed that thought suppression was positively correlated with rsFC between the right SFG and the left middle temporal gyrus (MTG). Interestingly, the relationship between neuroticism and thought suppression was mediated by the strength of rsFC between the right SFG and the left MTG. The results suggest that better ability to suppress unwanted intrusive thoughts is supported by greater GMV of the right SFG and stronger functional connectivity between the SFG and MTG. They also indicate that weak rsFC between the SFG and MTG can partly explain the negative association between neuroticism and thought suppression.
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