ArticleSurgery today2022
Impact of postoperative complications on the long-term outcome in lung cancer surgery.
Article in Surgery today, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Lobectomy versus segmentectomy for stage IA3 (T1cN0M0) non-small cell lung cancer: a meta-analysis and systematic review.Frontiers in oncology · 2023Pooled it
- Prognostic ımpact of vascular, lymphatic, and perineural ınvasion in surgically resected, non-adjuvantly treated stage IA non-small-cell lung cancer: a retrospective cohort study.Updates in surgery · 2026Article
- Pre-weekend effect in pulmonary resection for non-small cell lung cancer: a multicenter retrospective cohort study.Surgery today · 2026Observational
- Association between diaphragm thickness and postoperative complications in elderly patients with non-small-cell lung cancer.Surgery today · 2026Article
- Development and validation of a machine learning model to predict early recurrence after surgery in NSCLC patients.Scientific reports · 2025Article
- Development and validation of an explainable machine learning model for predicting postoperative pulmonary complications after lung cancer surgery: a machine learning study.EClinicalMedicine · 2025Article
- Impact of Intraoperative Dexamethasone on Postoperative Complications and Long-Term Survival in Patients with Non-Small Cell Lung Cancer: A retrospective Propensity Score-Matched Study.International journal of general medicine · 2025Article
- Systematic review and meta-analysis of breathing exercises effects on lung function and quality of life in postoperative lung cancer patients.Journal of thoracic disease · 2024Article
- Predicting complication risks after sleeve lobectomy for non-small cell lung cancer.Translational lung cancer research · 2024Article
- Multi-Modal Prehabilitation in Thoracic Surgery: From Basic Concepts to Practical Modalities.Journal of clinical medicine · 2024Review
- Risk factors for postoperative pulmonary infections in non-small cell lung cancer: a regression-based nomogram prediction model.American journal of cancer research · 2024Article
- Global trends and research hotspots in perioperative management of lung cancer: a bibliometric analysis from 2004 to 2024.Frontiers in immunology · 2024Article
- Comparison of Robotic and Open Lobectomy for Lung Cancer in Marginal Pulmonary Function Patients: A Single-Centre Retrospective Study.Current oncology (Toronto, Ont.) · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePostoperative complications have a significant impact on perioperative outcomes; however, their association with the long-term prognosis remains unclear. We evaluated the impact of postoperative complications on the long-term outcomes after curative surgery in lung cancer patients.
methodsThis study included 1129 patients with primary lung cancer who underwent lobectomy between April 2011 and March 2017. Univariate and multivariate analyses were performed to assess the association of postoperative complications with the overall and recurrence-free survival.
resultsPostoperative complications were observed in 147 (13.0%) patients over a median follow-up period of 5-years. Compared to patients without complications, those with complications showed had worse long-term outcomes, including the 5-year overall survival (75.3% vs. 86.1%, p < 0.001) and 5-year recurrence-free survival (64.2% vs. 74.4%, p = 0.004). A multivariate analysis revealed that the incidence of postoperative complications was significantly associated with the overall survival (hazard ratio = 1.665, p = 0.006) and recurrence-free survival (hazard ratio = 1.416, p = 0.025) in all patients. The prognostic influence was greater in patients with pathological stages II and III cancer (overall survival: hazard ratio = 2.019, p = 0.005; recurrence-free survival: hazard ratio = 1.90, p = 0.001) than in those with pathological stage I cancer.
conclusionPostoperative complications are independent predictors of the overall and recurrence-free survival in lung cancer patients, especially advanced-stage cancer patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.