Evidence map›Paper›PMID 35040934›Full record

ReviewBiology of reproduction2022

Preserving Oocytes in Oncofertility†.

Maria McClam, Shuo Xiao

Open access · bronzeAbstract readReview
In one paragraph

Review in Biology of reproduction, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

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  19. Fertility options after chemotherapy in young premenopausal patients.Acta endocrinologica (Bucharest, Romania : 2005)
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Maria McClamDepartment of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Shuo XiaoDepartment of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Environmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA.
Environmental and Occupational Health Sciences Institute · USUniversity of South Carolina · US

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
The effects of climate change on the natural attenuation and sedimentary record of harmful algal bloom toxins and microbial signalsP01ES028942 · NIEHS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI NORMAN, ROBERT SEAN · 2018 to 2022
$5.7M
PCOS and androgen-related disease modeling and drug testing in Multi-organ Integrated Microfluidic Reproductive PlatformUH3ES029073 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, JI-YONG JULIE · 2019 to 2021
$3.6M
Ovarian impacts of extreme heat and co-exposure to climate change-induced harmful algal bloom toxins (Admin Supplement to R01ES032144)R01ES032144 · NIEHS · RUTGERS, THE STATE UNIV OF N.J. · PI XIAO, SHUO · 2021 to 2025
$2.2M
Development of a High-Throughput Platform for Screening Ovotoxic Chemicals (K01ES030014)K01ES030014 · NIEHS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI XIAO, SHUO · 2019 to 2021
$490k
NIEHS NIH HHS K01 ES030014NIEHS NIH HHS P01 ES028942NIEHS NIH HHS P30 ES005022NIEHS NIH HHS R01 ES032144NIEHS NIH HHS UH3 ES029073
6 · The paper itself

Abstract

The prodigious rise of cancer survival rates enables many cancer survivors to live long lives. Therefore, the side effects of cancer treatments as well as the long-term quality of life after cancer have become more relevant. Ovarian toxicity is a major off-target effect of anticancer agents for childhood and young adult female cancer patients. Both chemotherapy and irradiation have been demonstrated to damage the ovary and increase the risks of premature ovarian failure (POF), early menopause, ovarian endocrine disorders, and sub- or infertility. Oncofertility is an emerging and multidisciplinary research and medical field that focuses on providing cancer patients with fertility preservation options. Oocyte quality and quantity are one of the most important factors to determine women's fertility success; therefore, preserving oocytes is paramount for maintaining the ability of young female cancer patients' reproduction after their recovery. This review summarizes peer-reviewed literature on current oocyte preservation options in oncofertility. We describe in-depth oocyte and embryo cryopreservation, ovarian suppression, ovarian tissue cryopreservation, in vitro maturation, ovarian transposition, and adjuvant therapy. Further, we discuss current guidelines and practices of female fertility preservation that cover preserving oocytes.

Indexed as

Fertility PreservationNeoplasmsChildCryopreservationFemaleHumansOocytesOvaryQuality of Lifecancerfertility preservationfollicleoncofertilityoocyteovary

Identifiers

PMID35040934
PMCPMC8862718
OpenAlexW4206828432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.