Evidence map›Paper›PMID 35040735›Full record

ArticleInternational journal of STD & AIDS2022

The prevalence and incidence of HIV in the ART era (2006-2016) in North West Tanzania.

Neema R Mosha, Jim Todd, Crispin Mukerebe, Milly Marston, Soledad Colombe, Benjamin Clark, James Beard, Baltazar Mtenga, Emma Slaymaker, Ties Boerma and 2 more

Abstract read
In one paragraph

Article in International journal of STD & AIDS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Neema R MoshaDivision of Epidemiology and Biostatistics, Faculty of Medicine and Health Sciences, 121470Stellenbosch University, Cape Town, South Africa.ORCID 0000-0002-5943-9494
Jim Todd119151National Institute for Medical Research, Mwanza Centre, Mwanza, Tanzania.
Crispin Mukerebe119151National Institute for Medical Research, Mwanza Centre, Mwanza, Tanzania.
Milly MarstonDepartment of Population Health, 4906London School of Hygiene and Tropical Medicine, London, UK.
Soledad Colombe25545Public Health Agency of Sweden, Solna, Sweden.
Benjamin ClarkDepartment of Population Health, 4906London School of Hygiene and Tropical Medicine, London, UK.
James BeardDepartment of Population Health, 4906London School of Hygiene and Tropical Medicine, London, UK.
Baltazar Mtenga119151National Institute for Medical Research, Mwanza Centre, Mwanza, Tanzania.
Emma SlaymakerDepartment of Population Health, 4906London School of Hygiene and Tropical Medicine, London, UK.
Ties BoermaUniversity of Manitoba, Winnipeg, MB, Canada.
Basia ZabaDepartment of Population Health, 4906London School of Hygiene and Tropical Medicine, London, UK.
Mark Urassa119151National Institute for Medical Research, Mwanza Centre, Mwanza, Tanzania.

Funding

Wellcome Trust 107754Wellcome Trust 107754/Z/15/Z
6 · The paper itself

Abstract

backgroundSub-Saharan countries bear a disproportionate percentage of HIV infections and HIV-related deaths despite the efforts to strengthen HIV prevention and treatments services, including ART. It is important to demonstrate how these services have contributed to reducing the epidemic using available population data.

methodsWe estimated the prevalence and incidence rates from a cohort running over 23 years in Magu District, Mwanza Region-North West Tanzania. Adults 15 years and over who were residents of the Kisesa observational HIV cohort study between 2006 and 2016 were eligible for inclusion. Survival analysis was used to calculate person-time at risk, incidence rates and 95% confidence intervals (CIs). Cox regression models were used for the risk factor analyses disaggregated by sex and age group.

resultsThe HIV prevalence in the sero-surveys decreased from 7.2% in 2006/07 to 6.6% in 2016, with a notable decrease of over 50% for both men and women aged 15-24 years. The incidence rate for HIV was estimated to be 5.5 (95% CI 4.6-6.6) per 1,000 person-years in women compared to 4.6 (95% CI 3.5-5.8) in men, with a decrease over time. Despite the availability of ART services, the uptake is still small.

conclusionsNew infections are still occurring, with high HIV incidence in individuals aged below 45 years. With new guidelines and the 95-95-95 UNAIDS target, prevalence and incidence must be adequately assessed. In addition, there is a need for additional efforts to assess the impact of HIV/AIDS prevention programmes and intervention services, especially in these areas where resources are limited.

Indexed as

HIV InfectionsAdolescentAdultCohort StudiesFemaleHumansIncidenceMaleMiddle AgedPrevalenceTanzaniaYoung AdultAIDSART (antiretroviral therapy)epidemiologyHIV (human immunodeficiency virus)otherviral disease

Identifiers

PMID35040735
PMCPMC7612632

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.