Evidence map›Paper›PMID 35040664›Full record

ArticleThe Journal of neuropsychiatry and clinical neurosciences2022

Treatment Patterns of Anxiety and Posttraumatic Stress Disorder Following Traumatic Brain Injury.

Madeline R Marks, Moira C Dux, Vani Rao, Jennifer S Albrecht

Abstract read
In one paragraph

Article in The Journal of neuropsychiatry and clinical neurosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Madeline R MarksThe Department of Psychiatry, University of Maryland School of Medicine, Baltimore (Marks); Neuropsychology Section, Veterans Affairs Maryland Health Care System, Baltimore (Dux); Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (Rao); Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore (Albrecht); and OptumLabs, Eden Prairie, Minn. (Albrecht).
Moira C DuxThe Department of Psychiatry, University of Maryland School of Medicine, Baltimore (Marks); Neuropsychology Section, Veterans Affairs Maryland Health Care System, Baltimore (Dux); Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (Rao); Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore (Albrecht); and OptumLabs, Eden Prairie, Minn. (Albrecht).
Vani RaoThe Department of Psychiatry, University of Maryland School of Medicine, Baltimore (Marks); Neuropsychology Section, Veterans Affairs Maryland Health Care System, Baltimore (Dux); Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (Rao); Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore (Albrecht); and OptumLabs, Eden Prairie, Minn. (Albrecht).
Jennifer S AlbrechtThe Department of Psychiatry, University of Maryland School of Medicine, Baltimore (Marks); Neuropsychology Section, Veterans Affairs Maryland Health Care System, Baltimore (Dux); Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore (Rao); Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore (Albrecht); and OptumLabs, Eden Prairie, Minn. (Albrecht).ORCID 0000-0003-4838-2274
University of Maryland, Baltimore · US

Funding

Prioritizing Quality Improvement for the Treatment of Psychiatric Disturbances Following Traumatic Brain InjuryK01HS024560 · AHRQ · UNIVERSITY OF MARYLAND BALTIMORE · PI ALBRECHT, JENNIFER S. · 2016 to 2020
$735k
AHRQ HHS K01 HS024560
6 · The paper itself

Abstract

objectiveSymptoms of mental disorders are common, are underrecognized, and contribute to worse outcomes after traumatic brain injury (TBI). Post-TBI, prevalence of anxiety disorders and prevalence of posttraumatic stress disorder (PTSD) are comparable with that of depression, but evidence-based treatment guidelines are lacking. The investigators examined psychotropic medication use and psychotherapy patterns among individuals diagnosed with anxiety disorders and PTSD post-TBI.

methodsAdministrative claims data were used to compare the prevalence and patterns of pharmacotherapy and psychotherapy utilization among individuals diagnosed with an anxiety disorder or PTSD post-TBI.

resultsAmong 207,354 adults with TBI, prevalence of anxiety disorders was 20.5%, and prevalence of PTSD was 0.6% post-TBI. Receipt of pharmacotherapy pre- and post-TBI (anxiety: pre-TBI=58.4%, post-TBI=76.2%; PTSD: pre-TBI=53.7%, post-TBI=75.2%) was considerably more common than receipt of psychotherapy (anxiety: pre-TBI=5.8%, post-TBI=19.1%; PTSD: pre-TBI=11.2%, post-TBI=36.0%). Individuals diagnosed with anxiety were 66% less likely to receive psychotherapy compared with individuals diagnosed with PTSD, although engagement in psychotherapy decreased faster over time among those with PTSD. Overall, psychotropic medication use and rates of antidepressant prescription use in the anxiety group were higher compared with those in the PTSD group. Benzodiazepines were the second most commonly prescribed medication class in the anxiety group, even though judicious use is warranted post-TBI.

conclusionsFurther exploration of differences and risks associated with pharmacotherapy for anxiety and PTSD post-TBI is warranted to refine treatment guidelines. The low level of psychotherapy engagement suggests that barriers and facilitators to psychotherapy utilization post-TBI should be examined in future studies.

Indexed as

Brain Injuries, TraumaticChronic Traumatic EncephalopathyStress Disorders, Post-TraumaticAdultAnxietyAnxiety DisordersHumansPsychotropic DrugsPsychotropic DrugsAnxiety Disorders (Neuropsychiatric Aspects)Traumatic Brain Injury

Identifiers

PMID35040664
PMCPMC13592398
OpenAlexW4205697593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.