Evidence map›Paper›PMID 35040005›Full record

ArticleMolecular biology reports2022

Seasonal expression of extracellular signal regulated kinases in the colon of wild ground squirrels (Spermophilus dauricus).

Yue Song, Xiaoying Yang, Xueying Zhang, Jueyu Zhu, Yixin Chen, Fuli Gao, Haolin Zhang, Yingying Han, Qiang Weng, Zhengrong Yuan

Abstract read
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In one paragraph

Article in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Seasonal Variation in Gut Microbiota of the Wild Daurian Ground Squirrel (Animals : an open access journal from MDPI · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yue SongCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Xiaoying YangCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Xueying ZhangCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Jueyu ZhuCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Yixin ChenSchool of Information Science and Technology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Fuli GaoCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Haolin ZhangCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Yingying HanCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Qiang WengCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China.
Zhengrong YuanCollege of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, 100083, People's Republic of China. zryuan@bjfu.edu.cn.
Beijing Forestry University · CN

Funding

Fundamental Research Funds for the Central Universities 2018ZY21National College Students Innovation and Entrepreneurship Training Program 202010022079National Training Program of Innovation and Entrepreneurship for Undergraduates 202010022072
6 · The paper itself

Abstract

backgroundThe purpose of the experiment was to explore the localization and seasonal expression of extracellular signal regulated kinase (ERK) in the colonic tissue of wild ground squirrels (Spermophilus dauricus). METHODS AND

resultsHematoxylin-eosin staining, immunohistochemistry, real-time quantitative PCR and Western blotting were used in this experiment. The histological results showed that the diameter of the colon lumen enlarged and the number of glandular cells increased in the non-breeding season. It was found in the immunochemical results that both ERK1/2 and pERK1/2 were expressed in the cytoplasm of goblet cells and intestinal epithelial cells, while pERK1/2 was also expressed in the nucleus of them. The immune localization of both was more obvious in the non-breeding season, especially in intestinal epithelial cells. Real-time quantitative PCR and Western blotting showed that ERK1/2 and pERK1/2 were seasonally highly expressed in the non-breeding season.

conclusionsThe expression of ERK1/2 and pERK1/2 was seasonal changes and had significant increases in the non-breeding season. This study revealed that ERK1/2 had potential roles in the colon to the adaptation of seasonal changes in wild ground squirrels.

Indexed as

Extracellular Signal-Regulated MAP KinasesSciuridaeAnimalsColonImmunohistochemistrySeasonsExtracellular Signal-Regulated MAP KinasesColonExtracellular signal regulated kinaseSeasonal adaptationWild ground squirrel

Identifiers

PMID35040005
OpenAlexW4225650818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.