Evidence map›Paper›PMID 35040001›Full record

Trial reportJournal of autism and developmental disorders2022

A Longitudinal RCT of P-ESDM With and Without Parental Mindfulness Based Stress Reduction: Impact on Child Outcomes.

Amy S Weitlauf, Neill Broderick, J Alacia Stainbrook, James C Slaughter, Julie Lounds Taylor, Catherine G Herrington, Amy G Nicholson, Madeline Santulli, Kristin Dorris, LaTamara Jackson Garrett and 7 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of autism and developmental disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03889821 (Does Mindfulness Training Enhance Early Evidence-based Parent-coaching Interventions for Autism Spectrum Disorder?), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03889821 nacompletednot on this map

Does Mindfulness Training Enhance Early Evidence-based Parent-coaching Interventions for Autism Spectrum Disorder?: A Randomized Controlled Trial

TypeinterventionalSponsorVanderbilt University Medical CenterRan2015 to 2018Enrolled63ConditionsAutism Spectrum Disorder, Parents, StressArmsParent-implemented Early Start Denver Model, Mindfulness Based Stress Reduction
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Amy S WeitlaufDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA. amy.s.weitlauf@vumc.org.ORCID http://orcid.org/0000-0002-3904-6378
Neill BroderickDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
J Alacia StainbrookDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
James C SlaughterDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, USA.
Julie Lounds TaylorDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Catherine G HerringtonDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Amy G NicholsonDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Madeline SantulliDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Kristin DorrisDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
LaTamara Jackson GarrettDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Michelle HoptonDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Amy KinsmanDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Mary MortonDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Ashley VogelDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Elisabeth M DykensDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
A Pablo JuárezDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Zachary E WarrenDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt University Medical Center · USVanderbilt University · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NEUL, JEFFREY L · 2015 to 2019
$7.1M
Eunice Kennedy Shriver National Institute of Child Health and Human Development U54 HD08321HRSA R40MC27706NCATS NIH HHS 5UL1TR002243-03NCATS NIH HHS UL1 TR002243NICHD NIH HHS P50 HD103537NICHD NIH HHS U54 HD083211
6 · The paper itself

Abstract

This randomized controlled trial (NCT03889821) examined Mindfulness Based Stress Reduction (MBSR) in conjunction with the Parent-implemented Early Start Denver Model (P-ESDM). A previous report described improved metrics of parental distress (Weitlauf et al. in Pediatrics 145(Supplement 1):S81-S92, 2020). This manuscript examines child outcomes. 63 children with ASD (< 36 months) and their parents received 12 P-ESDM sessions. Half of parents also received MBSR. Longitudinal examination of whole sample means revealed modest improvements in autism severity, cognitive, and adaptive skills. There was not a significant time × group interaction for children whose parents received MBSR. Future work should examine more proximal markers of child or dyadic change to enhance understanding of the impact of providing direct treatment for parents as part of early intervention initiatives.

Indexed as

Autism Spectrum DisorderAutistic DisorderMindfulnessChildEarly Intervention, EducationalHumansParentsStress, PsychologicalAutism spectrum disorderMindfulnessP-ESDMYoung children

Identifiers

PMID35040001
PMCPMC9289080
OpenAlexW4205211969

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.