ArticleArchives of microbiology2022
Phenolic and flavonoid contents and antioxidant activity of an endophytic fungus Nigrospora sphaerica (EHL2), inhabiting the medicinal plant Euphorbia hirta (dudhi) L.
Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 50 citations in OpenAlex.
- Isolation, identification and biological evaluation of endophytic fungi from Andrographis paniculata with special reference to antioxidant, antimicrobial and anticancer activities.Archives of microbiology · 2026Article
- Antioxidant potential and metabolic profiling of Viola odorata and the endophytic Rhizobium sp. BR7.Biotechnology letters · 2026Article
- Biological Control and Growth-Promoting Potential of the Endophytic FungusJournal of fungi (Basel, Switzerland) · 2026Article
- Untapped microbial factories for next-generation therapeutics: Endophytic fungi of medicinal plants.Microbial cell factories · 2026Review
- Chemical and Biological Investigation of the EndophyticJournal of fungi (Basel, Switzerland) · 2026Article
- Bioactivity screening of endophytic fungi from Sterculia urens and GC-MS metabolites profiling of the potent isolate Chaetomium meridiolense.Scientific reports · 2026Article
- Virtual screening and molecular dynamics studies of antivenom using flavonoid compounds derived from Andrographis echioides.Scientific reports · 2025Article
- Scrutinizing harsh habitats endophytic fungi and their prospective effect on water-stressed maize seedlings.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Biosynthesis of silver nanoparticles by Talaromyces funiculosus for therapeutic applications and safety evaluation.Scientific reports · 2025Article
- 2,4-Di-tert-butylphenol from Endophytic FungiFrontiers in microbiology · 2025Article
- Low microbial diversity, yeast prevalence, and nematode-trapping fungal presence in fungal colonization and leaf microbiome of Serjania erecta.Scientific reports · 2024Article
- An Investigation of Quorum Sensing Inhibitors againstMarine drugs · 2024Article
- Phytochemical Analysis and Antioxidant Activity of Endophytic Fungi Isolated from Dillenia indica Linn.Applied biochemistry and biotechnology · 2024Article
- Bioactivity-guided isolation of potential antidiarrheal constituents fromFrontiers in veterinary science · 2024Article
- Diversity analysis of endophytes with antimicrobial and antioxidant potential from Viola odorata: an endemic plant species of the Himalayas.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Two Novel Plant-Growth-PromotingPlants (Basel, Switzerland) · 2023Article
- Promising drought and salinity tolerance features of3 Biotech · 2023Article
- Bioactive compounds and biomedical applications of endophytic fungi: a recent review.Microbial cell factories · 2023Review
- Review
- Anti-multidrug-resistant Staphylococcus aureus and anti-dermatophyte activities of secondary metabolites of the endophytic fungus Penicillium brevicompactum ANT13 associated with the Algerian endemic plant Abies numidica.Archives of microbiology · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Since endophytic fungi are pivotal sources of various bioactive natural compounds, the present study is aimed to investigate the antioxidant compounds of the endophytic fungus Nigrospora sphaerica isolated from a pantropical weed, Euphorbia hirta L. The fungus was fermented in four different media and each filtered broth was sequentially extracted in various solvents. Crude extracts collected from different solvents were subjected to phytochemical analysis and antioxidant activity. The total phenolic content (TPC) and total flavonoid content (TFC) were maximal in ethyl acetate crude extract (EtOAcE) of endophyte fermented in potato dextrose broth (PDB) medium (77.74 ± 0.046mgGAE/g and 230.59 ± 2.0 mgRE/g) with the highest 96.80% antioxidant activity. However, TPC and TFC were absent in hexane extract of Czapek Dox broth (CDB) medium exhibiting the lowest 4.63 ± 2.75% activity. The EtOAcE (PDB) showed a positive correlation between TFC and antiradical activity (R
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