Evidence map›Paper›PMID 35039875›Full record

ArticleMolecular medicine reports2022

Epigallocatechin gallate enhances human lens epithelial cell survival after UVB irradiation via the mitochondrial signaling pathway.

Qiuxin Wu, Jike Song, Yan'e Gao, Yingying Zou, Junguo Guo, Xiuyan Zhang, Dongmei Liu, Dadong Guo, Hongsheng Bi

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Qiuxin WuAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Jike SongAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Yan'e GaoAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Yingying ZouAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Junguo GuoAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Xiuyan ZhangAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Dongmei LiuAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Dadong GuoCollege of Ophthalmology and Optometry, Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases, Shandong Academy of Eye Disease Prevention and Therapy, Jinan, Shandong 250002, P.R. China.
Hongsheng BiAffiliated Eye Hospital, Shandong University of Traditional Chinese Medicine, Jinan, Shandong 250002, P.R. China.
Shandong University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to explore the mechanism underlying the ultraviolet B (UVB) irradiation‑induced apoptosis of human lens epithelial cells (HLECs), and to investigate the protective effect of epigallocatechin gallate (EGCG) against the UVB‑induced apoptosis of HLECs. HLECs were exposed to different concentrations of EGCG plus UVB (30 mJ/cm

Indexed as

Ultraviolet RaysApoptosisBlotting, WesternCaspasesCatalaseCatechinCell LineCell SurvivalEpithelial CellsGene ExpressionHumansLens, CrystallineMitochondriaMolecular StructureOxidative StressProto-Oncogene Proteins c-bcl-2BCL2 protein, humanCaspasesCatalaseCatechinCAT protein, humanepigallocatechin gallateProto-Oncogene Proteins c-bcl-2Superoxide Dismutaseapoptosisepigallocatechin gallatehuman lens epithelial cellsultraviolet B

Identifiers

PMID35039875
PMCPMC8809122
OpenAlexW4205141051

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.