ArticleAesthetic surgery journal2022
Injection Guidelines for Treating Midface Volume Deficiency With Hyaluronic Acid Fillers: The ATP Approach (Anatomy, Techniques, Products).
Article in Aesthetic surgery journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Autologous Fat Grafting Versus Facial Fillers in Facial Cosmesis: A Systematic review and Meta-analysis.Aesthetic plastic surgery · 2026Pooled it
- Efficacy and safety of different hyaluronic acid fillers on cheek volume augmentation: systematic review and network meta-analysis.Archives of dermatological research · 2024Pooled it
- Debunking Myths on Hyaluronic Acid Injectable Gels in Clinical Practice.Plastic and reconstructive surgery. Global open · 2026Article
- Anatomical-based filler injection techniques for the midcheek groove and infraorbital region: Narrative review.JPRAS open · 2026Review
- Balanced Restoration: Optimizing Midface Rejuvenation Using Hyaluronic Acid Fillers.Plastic and reconstructive surgery. Global open · 2026Article
- V3 midface lifting through a subciliary approach: a three-vector physiologic repositioning technique for midface rejuvenation, lower eyelid support, and lower lid-malar contour improvement.Frontiers in surgery · 2026Article
- Creation and Validation of a Photonumeric Scale for Assessment of Midface Volume Deficit.Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2026Article
- Mastering Midface Rejuvenation: A Proposal for a New Three-Layer, Ultrasound-Guided Technique.Journal of cosmetic dermatology · 2026Article
- Hybrid Cooperative Complexes of Low- and High-Molecular-Weight Hyaluronic Acid in Aesthetic Medicine.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Depth and hemodynamics of the angular artery in the pyriform space: A cross-sectional study with Doppler ultrasonography.Imaging science in dentistry · 2025Article
- Morphometric effectiveness of calcium hydroxylapatite application in zygomatic and malar area on correction of nasolabial folds.Medicine · 2025Observational
- Anatomical-Based Filler Injection Techniques: Anteromedial, Buccal, and Lateral Cheek Hollow.Aesthetic plastic surgery · 2025Review
- Hyaluronic Acid Filler Usage and Technique for the Facial Upper Third: A Comprehensive Review.Plastic and reconstructive surgery. Global open · 2025Article
- Integrating Psychological Insights into Aesthetic Medicine: A Cross-Generational Analysis of Patient Archetypes (IMPACT Study).Aesthetic plastic surgery · 2025Article
- Safety and Performance of RHA4 in the Midface Using the Multilayering Technique: Preclinical and Clinical Evidence.Plastic and reconstructive surgery. Global open · 2025Article
- Article
- Optimizing Infraorbital Hollows Treatment With Hyaluronic Acid Fillers: Overview of Anatomy, Injection Techniques, and Product Considerations.Aesthetic surgery journal. Open forum · 2025Review
- Split-Face Comparison of Two Hyaluronic Acid Fillers: Intersection of Rheology and Tissue Behavior in Midface Rejuvenation.Aesthetic surgery journal. Open forum · 2025Article
- Effect of hyaluronic acid dermal fillers for mid-face volume enhancement: A systematic review and meta-analysis.Bioinformation · 2025Article
- New Aesthetic Unit (NAU) Method: A Comprehensive Method Based on Accurate Anatomical Assessment and Precise Multilayering Panfacial Treatment for Hyaluronic Acid Fillers.Aesthetic plastic surgery · 2024Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Midface rejuvenation is among the most valuable indications of hyaluronic acid dermal fillers, because malar projection and full upper cheeks significantly contribute to a youthful appearance. Hyaluronic acid fillers have evolved over the past 2 decades to meet specific clinical needs such as strong projection capacity and adaptability to facial dynamism. As a result, they now represent the treatment of choice for midface rejuvenation throughout age ranges by offering the potential for noninvasive treatment, immediate results, and minimal downtime. Because the 5-layered structure of the midface plays a central role in the human face, injecting the midface area may also indirectly improve other aesthetic concerns such as infraorbital hollowing and nasolabial folds. Nonetheless, midface rejuvenation requires a tailored treatment approach and a thorough knowledge of anatomy to minimize procedural risks and achieve natural-looking results. This article provides an extensive anatomical description of the midface and of the usual course and depth of vascular structures circulating nearby to delineate a treatment area and minimize procedural risks. Furthermore, considering the differential mobility and mechanical constraints of each layer of the midface, a multilayer treatment algorithm is proposed for adapting the treatment strategy to patient specificities (including age, gender, skin type, and morphology). Emphasis is also placed on desirable filler properties to create deep structural support on the one hand and accompany facial movement on the other hand.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.