ArticleScientific reports2022
Predicting ketosis during the transition period in Holstein Friesian cows using hematological and serum biochemical parameters on the calving date.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- Effects of boron and dicalcium phosphate supplementation on wool-biting behavior and metabolic indicators in lactating Akkaraman sheep.Tropical animal health and production · 2026Article
- Comparative effectiveness of propylene glycol-based health programs for controlling ketosis and improving performance in dairy cows.Veterinary world · 2026Article
- Thermoregulatory responses of ewes to winter shearing in mid- or late-pregnancy.Scientific reports · 2026Article
- Breed- and Parity-Associated Incidence and Manifestation of Metabolic Disorders in Holstein and Jersey Cows During the Postpartal Transition Period.Animals : an open access journal from MDPI · 2026Article
- Current Understanding of Bovine Ketosis: From Molecular Basis to Farm-Level Management.Animals : an open access journal from MDPI · 2025Review
- Foot-and-mouth disease adversely affects energy metabolism, surrogate indices of insulin resistance and milk yield till day 180 post-infection in the dairy cow.Tropical animal health and production · 2025Article
- Proinflammatory polarization of adipose tissue macrophages in cows with subclinical ketosis constitutes a critical driver of adipose tissue remodeling and inflammation.Journal of animal science and biotechnology · 2025Article
- Hepatocellular EVs Regulate Lipid Metabolism via SIRT1/SREBP-1c/PGC-1α Signaling in Primary Calf Hepatocytes.International journal of molecular sciences · 2025Article
- Changes in haematological and serum biochemical parameter concentrations from the day of calving to ketosis onset in Holstein dairy cows during the postpartum period.Irish veterinary journal · 2025Article
- Effects ofAnimals : an open access journal from MDPI · 2024Article
- The Effect of Subclinical Ketosis on the Peripheral Blood Mononuclear Cell Inflammatory Response and Its Crosstalk with Depot-Specific Preadipocyte Function in Dairy Cows.Animals : an open access journal from MDPI · 2024Article
- Clinical predictive significance of biomarker molecules elevation during the transition period in cattle suffering from different pathological states: A review.Open veterinary journal · 2024Review
- Article
- Effect of Parity, Body Condition Score at Calving, and Milk Yield on the Metabolic Profile of Gyr Cows in the Transition Period.Animals : an open access journal from MDPI · 2023Article
- Association between Tryptophan Metabolism and Inflammatory Biomarkers in Dairy Cows with Ketosis.Metabolites · 2023Article
- Comparison of blood gas parameters, ions, and glucose concentration in polish Holstein-Friesian Dairy cows at different milk production levels.Scientific reports · 2023Article
- Comparison of prepartum blood parameters in dairy cows with postpartum ketosis and new risk prediction candidates.Frontiers in veterinary science · 2023Article
- Characteristics of Holstein cows predisposed to ketosis during the post-partum transition period.Veterinary medicine and science · 2023Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Ketosis often occurs during the postpartum transition period in dairy cows, leading to economic and welfare problems. Previously, ketosis was reported to be associated with hematological and serum biochemical parameters. However, the association between the parameters on the calving date and ketosis during the postpartum transition period remains unclear. This study aimed to investigate this association. Blood samples were collected from the jugular vein of Holstein cows on the calving date and β-hydroxybutyrate was tested once every 3 days (8 times in 21 days). The cows were divided into three groups: non-ketosis, subclinical ketosis, and clinical ketosis. The clinical ketosis group significantly had the highest values of mean corpuscular volume, mean corpuscular hemoglobin, β-hydroxybutyrate, non-esterified fatty acids, and total bilirubin, but the lowest values of red cell distribution width, the counts of white blood cell, monocyte, and eosinophil, albumin, alanine transaminase, lactate dehydrogenase, and amylase. In contrast, the non-ketosis group showed the opposite results (p < 0.05). In conclusion, these parameters are associated with the development and severity of ketosis. Our findings suggest that these parameters on the calving date may be useful indicators to identify dairy Holstein cow susceptible to ketosis during the transition period.
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