Evidence map›Paper›PMID 35039078›Full record

ArticleBMC pharmacology & toxicology2022

Comparative risk of incidence and clinical outcomes of COVID-19 among proton pump inhibitor and histamine-2 receptor antagonist short-term users: a nationwide retrospective cohort study.

Jimyung Park, Seng Chan You, Jaehyeong Cho, Chan Hyuk Park, Woon Geon Shin, Rae Woong Park, Seung In Seo

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC pharmacology & toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Jimyung Park *Department of Biomedical Sciences, Ajou University Graduate School of Medicine, 164, World cup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16499, Republic of Korea.
Seng Chan You *Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jaehyeong ChoDepartment of Biomedical Sciences, Ajou University Graduate School of Medicine, 164, World cup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16499, Republic of Korea.
Chan Hyuk ParkDepartment of Internal Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.
Woon Geon ShinDivision of Gastroenterology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 150, Seongan-ro, Seoul, Gangdong-gu, 05355, South Korea.
Rae Woong Park *Department of Biomedical Sciences, Ajou University Graduate School of Medicine, 164, World cup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16499, Republic of Korea. veritas@ajou.ac.kr.
Seung In Seo *Division of Gastroenterology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 150, Seongan-ro, Seoul, Gangdong-gu, 05355, South Korea. doctorssi@kdh.or.kr.
Ajou University · KRHallym University · KRHanyang University Guri Hospital · KRKangdong Sacred Heart Hospital · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate incidence risk and adverse clinical outcomes in COVID-19 disease among short-term users of acid-suppressants in South Korea.

methodsThis retrospective cohort study, conducted using a nationwide claims database for South Korea, used data from patients with COVID-19 tested between January 1 and May 15, 2020. Patients aged over 18 years and prescribed proton pump inhibitors (PPI) or histamine-2 receptor antagonist (H

resultsWe identified 26,166 PPI users and 62,117 H

conclusionsIn this study, we found that the PPI user was not associated with risk of COVID-19 compared to H

Indexed as

SARS-CoV-2AdolescentAdultAgedAged, 80 and overCOVID-19FemaleHistamine H2 AntagonistsHospitalizationHumansIncidenceMaleMiddle AgedProton Pump InhibitorsRepublic of KoreaRetrospective StudiesHistamine H2 AntagonistsProton Pump InhibitorsAcid suppressantsEpidemiologyPharmacovigilanceRetrospective studies

Identifiers

PMID35039078
PMCPMC8762632
OpenAlexW4205685663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.