SynthesisBMC musculoskeletal disorders2022
Preoperative predictors of health-related quality of life changes (EQ-5D and EQ VAS) after total hip and knee replacement: a systematic review.
Synthesis in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Postoperative Rehabilitation Interventions in Patients at Risk of Poorer Outcomes Following Total Knee Arthroplasty: A Systematic Review.Musculoskeletal care · 2025Pooled it
- Effects of medical interventions on health-related quality of life in chronic disease - systematic review and meta-analysis of the 19 most common diagnoses.Frontiers in public health · 2024Pooled it
- Total hip arthroplasty restores population health-related quality of life norms : a propensity-matched study with mediation analysis of BMI.Bone & joint open · 2026Article
- Prediction of quality-of-life improvement after total hip arthroplasty : a simplified and internally validated model based on 82,526 total hip arthroplasties from the Swedish Arthroplasty Register.Bone & joint open · 2025Article
- Article
- Health-Related Quality of Life, Body Mass Index and the 10-Metre Walk Test in Patients Awaiting Total Knee or Hip Arthroplasty: A Cross-Sectional Data Analysis with Matched Controls.Life (Basel, Switzerland) · 2025Article
- Eight of ten patients return to daily activities, work, and sports after total knee arthroplasty.World journal of orthopedics · 2024Article
- May the 4th be with you: mixed-methods best-evidence synthesis on 4th-generation alumina-zirconia ceramic bearings in total hip arthroplasty.EFORT open reviews · 2024Article
- Does an Adductor Canal Block Influence Patient-Reported Outcomes at One Year Following Total Knee Arthroplasty?Cureus · 2023Article
- Chronic Vulvar Pain and Health-Related Quality of Life in Women with Vulvodynia.Life (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatient-reported outcomes are of ever-increasing importance in medical decision-making. The EQ-5D is one of the generic instruments measuring health-related quality of life (HRQoL) in arthroplasty. This review aimed to identify possible predictors of HRQoL changes for patients undergoing total knee replacements (TKR) or total hip replacements (THR).
methodsA systematic literature review according to the PRISMA guidelines was conducted, searching several databases. Preoperative to postoperative HRQoL changes were evaluated in patients undergoing THR or TKR, using the EQ-5D visual analog scale (VAS) or the preference-based EQ-5D Index were evaluated. Articles were considered with prospectively or retrospectively collected data, as well as registry data, each with statistical analyses of patient-related factors.
resultsEight hundred eighty-two articles were found, of which 21 studies met the inclusion criteria. Predictors were distinguished in alterable and non-alterable ones. The EQ-5D Index indicated a tendency towards beneficial improvements for patients with a high body mass index (BMI) (> 40) and no significant results for the VAS. Additionally, one study found that patient education and preoperative physiotherapy appeared to enhance HRQoL. Some evidence indicated that male gender was negatively associated with changes in the VAS and the EQ-5D Index, but one study reported the opposite. Changes in VAS and EQ-5D Index were lower for older patients, whereas a higher educational level seemed to be advantageous. A high Charnley class led to deteriorating changes in VAS, although a high Kellgren Lawrence classification was positively associated with the EQ-5D Index, in a limited number of studies. For all results, clinical relevance was calculated differently and mainly reported as uncertain or small.
conclusionsThe literature on this topic was weak and offers only limited guidance. Results for alterable predictors, such as the BMI, indicated valuable improvements for highly obese patients. Further, high-quality research is required to support medical decision-making. LEVEL OF EVIDENCE: Level IV, according to the OCEBM Levels of Evidence Working Group.
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