Evidence map›Paper›PMID 35038997›Full record

ArticleBMC public health2022

Healthy dietary patterns and metabolic dysfunction-associated fatty liver disease in less-developed ethnic minority regions: a large cross-sectional study.

Xiaofen Xie, Bing Guo, Xiong Xiao, Jianzhong Yin, Ziyun Wang, Xiaoman Jiang, Jingzhong Li, Lu Long, Junmin Zhou, Ning Zhang and 4 more

Abstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Metabolic diseases in the East Asian populations.Nature reviews. Gastroenterology & hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xiaofen Xie *West China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China.
Bing Guo *West China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China.
Xiong XiaoWest China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China.
Jianzhong YinSchool of Public Health, Kunming Medical University, Kunming, China.
Ziyun WangSchool of Public Health, the key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, China.
Xiaoman JiangChengdu Center for Disease Control and Prevention, Chengdu, China.
Jingzhong LiTibet Center for Disease Control and Prevention, Lhasa, China.
Lu LongWest China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China.
Junmin ZhouWest China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China.
Ning ZhangWest China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China.
Yuan ZhangWest China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China.
Ting Chen *Chongqing Municipal Center for Disease Control and Prevention, No.8, Changjiang 2nd Road, Chongqin, 400042, China. 640963985@qq.com.
Baima Kangzhuo *Tibet University, No.10, East Tibet University Road, Lhasa, 850000, China. bmkz123@163.com.
Xing Zhao *West China School of Public Health and West China Fourth Hospital, Sichuan University, No.16, People's South Road, Chengdu, 610041, China. xingzhao@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the associations between healthy dietary patterns and metabolic dysfunction-associated fatty liver disease (MAFLD) in less-developed ethnic minority regions (LEMRs), where the prevalence of MAFLD is increasing rapidly and dietary habits are quite different from those in developed countries. Moreover, a significant subset of MAFLD individuals in LEMRs are nonobese, but the efficacy of dietary patterns on MAFLD individuals with different obese statuses is also unclear. We aimed to test the associations of two wildly recommended a priori dietary patterns-Alternate Mediterranean diet (AMED) and Dietary Approaches to Stop Hypertension (DASH)-with the risk of MAFLD in the total population, and further in nonobese and obese individuals.

methodsWe recruited 99,556 participants in the China Multi-Ethnic Cohort Study, an ongoing cohort study in less-developed southwest China. Using validated food frequency questionnaire, each participant was assigned an AMED score and a DASH score. MAFLD was ascertained as hepatic steatosis on ultrasound together with diabetes, overweight/obesity, or two other metabolic risk factors. We performed logistic regression with inverse probability of exposure weighting (IPEW) to examine associations between two dietary patterns and MAFLD, adjusting for potential confounders under the guidance of directed acyclic graphs. Further, analyses were stratified by body mass index.

resultsWe included 66,526 participants (age 49.5±11.0; 62.6% women), and the prevalence of MAFLD was 16.1%. Participants in the highest quintile of DASH score showed strong inverse associations with risks of MAFLD (OR = 0.85; 95% CI, 0.80-0.91; P

conclusionsIn LEMRs, a DASH diet but not AMED was associated with MAFLD. The relationship appeared to be more pronounced in nonobese MAFLD individuals than in obese MAFLD individuals.

Indexed as

Diet, MediterraneanNon-alcoholic Fatty Liver DiseaseAdultCohort StudiesCross-Sectional StudiesEthnic and Racial MinoritiesEthnicityFemaleHumansMaleMiddle AgedMinority GroupsObesityDietary patternMAFLDMetabolicNAFLDObesity

Identifiers

PMID35038997
PMCPMC8764858

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.