Trial reportBMC psychiatry2022
In-office, in-home, and telehealth cognitive processing therapy for posttraumatic stress disorder in veterans: a randomized clinical trial.
Trial report in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02290847 (Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD), which is not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD
Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Effectiveness and moderators of PE and CPT in adult PTSD treatment: a systematic review and meta-analysis.European journal of psychotraumatology · 2026Pooled it
- Comparing Video-Based and Face-to-Face Psychotherapy: Systematic Review and Multilevel Meta-Analysis Across Mental Disorders.Journal of medical Internet research · 2026Pooled it
- A meta-analytic review of cognitive processing therapy with and without the written account.Journal of anxiety disorders · 2025Pooled it
- Opportunities and challenges in leveraging digital technology for mental health system strengthening: a systematic review to inform interventions in the United Arab Emirates.BMC public health · 2024Pooled it
- Therapist-guided remote versus in-person cognitive behavioural therapy: a systematic review and meta-analysis of randomized controlled trials.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024Pooled it
- Cognitive Processing Therapy for Posttraumatic Stress Disorder in Japan: A Randomized Clinical Trial.JAMA network open · 2025Trial
- The interactions between patient preferences, expectancies, and stigma contribute to posttraumatic stress disorder treatment outcomes.Journal of traumatic stress · 2023Trial
- Treating posttraumatic stress disorder at home in a single week using 1-week virtual massed cognitive processing therapy.Journal of traumatic stress · 2022Trial
- Effectiveness of massed cognitive processing therapy for posttraumatic stress disorder: A retrospective analysis.Journal of traumatic stress · 2026Article
- Mental health distress and associated factors among online CBT service users during the Iron Swords War.Frontiers in psychology · 2026Article
- Staying Relevant in the Digital Age: Exploring the Evolving Frontier of Telehealth for Mental Health in the Military Health System and Veterans Health Administration.Current psychiatry reports · 2025Review
- Perceptions of behavioral health care quality for justice-involved veterans: a multi-jurisdictional analysis of Veterans Treatment Court team insights.Health & justice · 2025Article
- The role of impulsivity in the association between rumination and cannabis-related problems among trauma-exposed cannabis users.The British journal of clinical psychology · 2025Article
- Enhancing massed prolonged exposure with cannabidiol to improve posttraumatic stress disorder: Design and methodology of a pilot randomized clinical trial.Contemporary clinical trials communications · 2024Article
- Impact and efficiency of treatment across two PTSD clinical trials comparing in-person and telehealth service delivery formats.Psychological services · 2024Article
- Treatment of Posttraumatic Stress Disorder: A State-of-the-art Review.Current neuropharmacology · 2024Review
- Psychiatric Treatment Conducted via Telemedicine Versus In-Person Modality in Posttraumatic Stress Disorder, Mood Disorders, and Anxiety Disorders: Systematic Review and Meta-Analysis.JMIR mental health · 2023Review
- An open trial of VA CONNECT: Caring for Our Nation's Needs Electronically during the COVID-19 Transition.Psychiatry research communications · 2023Article
- Impact of morally injurious traumatic event exposure on cognitive processing therapy outcomes among Veterans and service members.Journal of military, veteran and family health · 2023Article
- Aerobic exercise improves sleep in U. S. active duty service members following brief treatment for posttraumatic stress disorder symptoms.Frontiers in psychology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrauma-focused psychotherapies for combat-related posttraumatic stress disorder (PTSD) in military veterans are efficacious, but there are many barriers to receiving treatment. The objective of this study was to determine if cognitive processing therapy (CPT) for PTSD among active duty military personnel and veterans would result in increased acceptability, fewer dropouts, and better outcomes when delivered In-Home or by Telehealth as compared to In-Office treatment.
methodsThe trial used an equipoise-stratified randomization design in which participants (N = 120) could decline none or any 1 arm of the study and were then randomized equally to 1 of the remaining arms. Therapists delivered CPT in 12 sessions lasting 60-min each. Self-reported PTSD symptoms on the PTSD Checklist for DSM-5 (PCL-5) served as the primary outcome.
resultsOver half of the participants (57%) declined 1 treatment arm. Telehealth was the most acceptable and least often refused delivery format (17%), followed by In-Office (29%), and In-Home (54%); these differences were significant (p = 0.0008). Significant reductions in PTSD symptoms occurred with all treatment formats (p < .0001). Improvement on the PCL-5 was about twice as large in the In-Home (d = 2.1) and Telehealth (d = 2.0) formats than In-Office (d = 1.3); those differences were statistically large and significant (d = 0.8, 0.7 and p = 0.009, 0.014, respectively). There were no significant differences between In-Home and Telehealth outcomes (p = 0.77, d = -.08). Dropout from treatment was numerically lowest when therapy was delivered In-Home (25%) compared to Telehealth (34%) and In-Office (43%), but these differences were not statistically significant.
conclusionsCPT delivered by telehealth is an efficient and effective treatment modality for PTSD, especially considering in-person restrictions resulting from COVID-19.
trial registrationClinicalTrials.gov ID NCT02290847 (Registered 13/08/2014; First Posted Date 14/11/2014).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.