Evidence map›Paper›PMID 35038924›Full record

ArticlemBio2022

Comparative Genomics of Borderline Oxacillin-Resistant Staphylococcus aureus Detected during a Pseudo-outbreak of Methicillin-Resistant S. aureus in a Neonatal Intensive Care Unit.

Sanjam S Sawhney, Eric M Ransom, Meghan A Wallace, Patrick J Reich, Gautam Dantas, Carey-Ann D Burnham

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Mislocalization of PBPs inMicrobiology spectrum · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Antimicrobial Resistance Patterns ofAntibiotics (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Low prevalence of borderline oxacillin resistantInfection prevention in practice · 2024
    Article
  10. Article
  11. Case Commentary: The hidden side of oxacillin resistance inAntimicrobial agents and chemotherapy · 2023
    Article
  12. Failure ofAntimicrobial agents and chemotherapy · 2023
    Article
  13. Identification ofAntibiotics (Basel, Switzerland) · 2022
    Article
  14. Current Methods for Recombination Detection in Bacteria.International journal of molecular sciences · 2022
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sanjam S Sawhney *The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-5343-1224
Eric M Ransom *Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Meghan A WallaceDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
Patrick J ReichDepartment of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.
Gautam DantasThe Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0003-0455-8370
Carey-Ann D BurnhamDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0002-1137-840X
Washington University in St. Louis · US

Funding

TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGYT32GM007067 · NIGMS · WASHINGTON UNIVERSITY · PI TRUE-KROB, HEATHER L · 1985 to 2020
$20.4M
Impact of early-life perturbations on pediatric microbiome maturationR01AI155893 · NIAID · WASHINGTON UNIVERSITY · PI Gautam Dantas · 2021 to 2026
$4.6M
PHYLOGENOMIC, TRANSCRIPTOMIC, VIROMIC, AND IMMUNOPROTEOMIC DETERMINANTS OF NECROTIZING ENTEROCOLITISR01HD092414 · NICHD · WASHINGTON UNIVERSITY · PI DANTAS, GAUTAM, TARR, PHILLIP I · 2017 to 2021
$3.0M
NIAID NIH HHS R01 AI155893NICHD NIH HHS R01 HD092414NIGMS NIH HHS T32 GM007067
6 · The paper itself

Abstract

Active surveillance for methicillin-resistant Staphylococcus aureus (MRSA) is a component of our neonatal intensive care unit (NICU) infection prevention efforts. Recent atypical trends prompted review of 42 suspected MRSA isolates. Species identification was confirmed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), and methicillin resistance was reevaluated by PBP2a lateral flow assay, cefoxitin/oxacillin susceptibility testing,

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCefoxitinGenomicsHumansInfant, NewbornIntensive Care Units, NeonatalMethicillin ResistanceMicrobial Sensitivity TestsOxacillinPenicillin-Binding ProteinsStaphylococcus aureusAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesCefoxitinOxacillinPenicillin-Binding ProteinsBORSAchromogenic agarschromogenic mediagdpPMRSANGSoxacillinrandom forest classifierStaphylococcus aureussurveillance culturessurveillance studiessusceptibility testingWGS

Identifiers

PMID35038924
PMCPMC8764539
OpenAlexW4205800034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.