Evidence map›Paper›PMID 35038905›Full record

ArticlemBio2022

Sayed Golam Mohiuddin, Aslan Massahi, Mehmet A Orman

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Glycerol-Driven Energy and Proteostasis Underpin Antibiotic Tolerance inbioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Proteostasis-targeted antibacterial strategies.Journal of microbiology (Seoul, Korea) · 2026
    Review
  7. Characterization ofMicroorganisms · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sayed Golam Mohiuddin *Department of Chemical and Biomolecular Engineering, University of Houstongrid.266436.3, Houston, Texas, USA.
Aslan Massahi *Department of Chemical and Biomolecular Engineering, University of Houstongrid.266436.3, Houston, Texas, USA.
Mehmet A OrmanDepartment of Chemical and Biomolecular Engineering, University of Houstongrid.266436.3, Houston, Texas, USA.ORCID 0000-0001-8499-9154
University of Houston · US

Funding

Characterizing a Self-Digesting-Mediated Reversible Drug Tolerance Mechanism in BacteriaR01AI143643 · NIAID · UNIVERSITY OF HOUSTON · PI ORMAN, MEHMET A. · 2020 to 2024
$1.9M
Investigating "viable but non-culturable" Cell and Persister Formation MechanismsK22AI125468 · NIAID · UNIVERSITY OF HOUSTON · PI ORMAN, MEHMET A. · 2018 to 2019
$270k
NIAID NIH HHS K22 AI125468NIAID NIH HHS R01 AI143643
6 · The paper itself

Abstract

Bacterial persisters are nongrowing cells highly tolerant to bactericidal antibiotics. However, this tolerance is reversible and not mediated by heritable genetic changes. Lon, an ATP-dependent protease, has repeatedly been shown to play a critical role in fluoroquinolone persistence in Escherichia coli. Although

Indexed as

Escherichia coli ProteinsProtease LaAnti-Bacterial AgentsATP-Dependent ProteasesBacteriaEscherichia coliFluoroquinolonesAnti-Bacterial AgentsATP-Dependent ProteasesEscherichia coli ProteinsFluoroquinolonesLon protein, E coliProtease LaEscherichia coliLon proteaseofloxacinpersistersresuscitationZ-ring

Identifiers

PMID35038905
PMCPMC8764555
OpenAlexW4220852783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.