Evidence map›Paper›PMID 35038901›Full record

ArticlemBio2022

Quorum Sensing Promotes Phage Infection in Pseudomonas aeruginosa PAO1.

Guanhua Xuan, Hong Lin, Lin Tan, Gang Zhao, Jingxue Wang

Open access · goldAbstract read
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 48 citations in OpenAlex.

  1. Multifaceted effects ofVirulence · 2026
    Article
  2. Review
  3. From screening to treatment:Microbiology spectrum · 2026
    Article
  4. Article
  5. Article
  6. Phages and quorum sensing: findings to consider in phage therapy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Phage-host interaction inApplied and environmental microbiology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Understanding phage BX-1 resistance inMicrobiology spectrum · 2025
    Article
  17. CombatingFrontiers in cellular and infection microbiology · 2025
    Review
  18. Article
  19. Quorum sensing positively regulates CPS-dependentApplied and environmental microbiology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Guanhua XuanFood Safety Laboratory, College of Food Science and Engineering, Ocean University of Chinagrid.4422.0, Qingdao, China.
Hong LinFood Safety Laboratory, College of Food Science and Engineering, Ocean University of Chinagrid.4422.0, Qingdao, China.
Lin TanFood Safety Laboratory, College of Food Science and Engineering, Ocean University of Chinagrid.4422.0, Qingdao, China.
Gang ZhaoFood Safety Laboratory, College of Food Science and Engineering, Ocean University of Chinagrid.4422.0, Qingdao, China.
Jingxue WangFood Safety Laboratory, College of Food Science and Engineering, Ocean University of Chinagrid.4422.0, Qingdao, China.
Ocean University of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quorum sensing (QS) is used to coordinate social behaviors, such as virulence and biofilm formation, across bacterial populations. However, the role of QS in regulating phage-bacterium interactions remains unclear. Preventing phage recognition and adsorption are the first steps of bacterial defense against phages; however, both phage recognition and adsorption are a prerequisite for the successful application of phage therapy. In the present study, we report that QS upregulated the expression of phage receptors, thus increasing phage adsorption and infection rates in Pseudomonas aeruginosa. In P. aeruginosa PAO1, we found that

Indexed as

Pseudomonas InfectionsQuorum SensingAnti-Bacterial AgentsBacterial ProteinsBiofilmsHumansLipopolysaccharidesPseudomonas aeruginosaVirulence FactorsAnti-Bacterial AgentsBacterial ProteinsLipopolysaccharidesVirulence FactorsadsorptiongalUlas quorum sensinglipopolysaccharideP. aeruginosaphage

Identifiers

PMID35038901
PMCPMC8764535
OpenAlexW4206331765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.