Evidence map›Paper›PMID 35038791›Full record

ArticleESC heart failure2022

Anatomical and histological assessment of left bundle branch area pacing in human heart with refractory heart failure.

Jiefang Zhang, Yiwen Pan, Yaxun Sun, Guosheng Fu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiefang ZhangDepartment of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University of Medicine, Hangzhou, Zhejiang, 310016, China.ORCID 0000-0002-0327-1987
Yiwen PanDepartment of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University of Medicine, Hangzhou, Zhejiang, 310016, China.
Yaxun SunDepartment of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University of Medicine, Hangzhou, Zhejiang, 310016, China.
Guosheng FuDepartment of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University of Medicine, Hangzhou, Zhejiang, 310016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an emerging pacing technique, left bundle branch area pacing (LBBAP) has served as a physiological pacing modality that overcomes the limitations of His bundle pacing (HBP) or right ventricular pacing. Three patients with terminal heart failure who were waiting for heart transplantation and met the indications of pacemaker implantations received LBBAP. Symptoms were relieved and stabilized and eventually received heart transplantation. Diseased hearts from the recipients were dissected post-transplantation, and the direct visual of pacing lead locations in the interventricular septum were evaluated, and the histopathological examination around the lead was conducted for the first time in human. As a result, we found that the locations of LBBAP leads were matched with fluoroscopic views during the procedure and Masson's staining showed extensive fibrosis occur around the lead but did not result in high thresholds.

Indexed as

Bundle of HisHeart FailureCardiac Pacing, ArtificialElectrocardiographyHeart Conduction SystemHumansAnatomical assessmentHistopathological evaluationLeft bundle branch area pacingRefractory heart failure

Identifiers

PMID35038791
PMCPMC8934916

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.