Evidence map›Paper›PMID 35038668›Full record

ArticleJournal of infection and public health2022

Evaluation of the diagnostic capacities for emerging arboviral diseases in the international network MediLabSecure from 2014 to 2018 - Importance of external quality assessments.

Guillain Mikaty, Séverine Matheus, Oliver Donoso Mantke, Elaine McCulloch, Heinz Zeichhardt, Jean-Claude Manuguerra, MediLabSecure

Open access · goldAbstract read
In one paragraph

Article in Journal of infection and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Guillain MikatyInstitut Pasteur, Université de Paris, Environment and Infectious Risk research Unit - Laboratory for Urgent Response to Biological Threats (ERI-CIBU), Paris, France. Electronic address: guillain.mikaty@pasteur.fr.
Séverine MatheusInstitut Pasteur, Université de Paris, Environment and Infectious Risk research Unit - Laboratory for Urgent Response to Biological Threats (ERI-CIBU), Paris, France.
Oliver Donoso MantkeQuality Control for Molecular Diagnostics (QCMD), Glasgow, United Kingdom.
Elaine McCullochQuality Control for Molecular Diagnostics (QCMD), Glasgow, United Kingdom.
Heinz ZeichhardtINSTAND; Gesellschaft zur Förderung der Qualitätssicherung in medizinischen Laboratorien e.V., Düsseldorf, Germany.
Jean-Claude ManuguerraInstitut Pasteur, Université de Paris, Environment and Infectious Risk research Unit - Laboratory for Urgent Response to Biological Threats (ERI-CIBU), Paris, France.
MediLabSecure
Institut Pasteur · FRBQS Institut für Qualität und Patientensicherheit (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEmerging infectious diseases pose an increasing threat to all nations around the world, including to developed countries. By definition, because they are rare or unknown, public health systems are not well prepared against these emerging diseases. To be fully prepared, countries must have implemented surveillance systems to monitor rare or unusual sanitary events.

methodsThe capacity of diagnostic laboratories is a key component of surveillance systems since they are in charge of identifying the pathogens responsible for outbreaks in a timely manner. The MediLabSecure project aims at implementing a comprehensive surveillance system for vector-borne diseases around the Mediterranean and Black Sea regions. From 2014 to 2018, the human-virology group of MediLabSecure notably supported the implementation of molecular diagnostic capacities for eight arboviruses and one coronavirus in 19 laboratories of its network through sharing of protocols and reagents, and technical training of the scientific staff of beneficiary laboratories.

resultsWe report the results of External Quality Assessments for four of these viruses to assess the efficiency of the diagnostic for these threats emerging in the geographic area. The results for these EQA demonstrate the success of the project in the implementation of diagnostic technics for the identification of Dengue, Chikungunya, Zika, and West Niles viruses in laboratories that did not have the capacity before. However, results also show that some work is still to be done to strengthen the newly acquired capacity.

conclusionThe MediLabSecure project deployed an effort to build an efficient capacity in identifying and survey the emergence of arboviruses in the Mediterranean area. Diagnostic technics were successfully implemented in many of the laboratories of the network, but the effort must be maintained over time to strengthen these capacities.

Indexed as

ArbovirusesArbovirus InfectionsChikungunya FeverZika VirusZika Virus InfectionHumansArbovirusesExternal quality assessment (EQA)MediLabSecureMolecular diagnosticSurveillance

Identifiers

PMID35038668
PMCPMC8656250
OpenAlexW4200402198

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.