SynthesisPublic health2022
Asymptomatic infection and transmission of COVID-19 among clusters: systematic review and meta-analysis.
Synthesis in Public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Estimating Hidden Population Size of COVID-19 using Respondent-Driven Sampling Method - A Systematic Review.Infectious disorders drug targets · 2024Pooled it
- Pooled it
- Air Passengers' Risk of SARS-CoV-2 Infection With a 14-Day Quarantine and Accuracy Assessment of a Symptom-based Screening System at an Airport.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025Article
- In silico prediction of pathogen's pandemic potential using the viral trait assessment for pandemics (ViTAP) model.PNAS nexus · 2024Article
- Characteristics of Lung Cancer Patients With Asymptomatic or Undiagnosed SARS-CoV-2 Infections.Clinical lung cancer · 2024Article
- A vaccination-based COVID-19 model: Analysis and prediction using Hamiltonian Monte Carlo.Heliyon · 2024Article
- Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detection Techniques, and Post-Pandemic Treatment Strategies.International journal of molecular sciences · 2024Review
- Asymptomatic Children as a Missing Link in Preventing COVID-19 Transmission.Journal of research in health sciences · 2024Article
- COVID-19 monitoring of school personnel through molecular salivary test and dried blood spot analysis.Journal of global health · 2024Article
- Sudden sensorineural hearing loss: audiological profile during the COVID-19 pandemic.Frontiers in neurology · 2024Article
- Seroprevalence of SARS-CoV-2 infection in pediatric patients in a tertiary care hospital setting.PloS one · 2024Article
- Civil Society Involvement in Managing the COVID-19 Pandemic: A Case Study of a Large and Congested Urban Community in Bangkok, Thailand.Health equity · 2024Article
- Article
- Demographic Characteristics of Unvaccinated Asymptomatic and Symptomatic SARS-CoV-2 Cases in Barwon South West, Victoria, Australia.Pathogens (Basel, Switzerland) · 2023Article
- Transmission dynamics, responses, and clinical features for the first 1100 COVID-19 cases in South Batinah, Oman: Major lessons from a provincial perspective.Journal of Taibah University Medical Sciences · 2023Article
- Assessing risk of major adverse cardiac event among COVID-19 patients using HEART score.Internal and emergency medicine · 2023Observational
- Patterns of SARS-CoV-2 circulation revealed by a nationwide sewage surveillance programme, the Netherlands, August 2020 to February 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Article
- Article
- What is the burden of asymptomatic coronavirus infections?New microbes and new infections · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCountries throughout the world are experiencing COVID-19 viral load in their populations, leading to potential transmission and infectivity of asymptomatic COVID-19 cases. The current systematic review and meta-analysis aims to investigate the role of asymptomatic infection and transmission reported in family clusters, adults, children and health care workers, globally. STUDY
designSystematic review and meta-analysis.
methodsAn online literature search of PubMed, Google Scholar, medRixv and BioRixv was performed using standard Boolean operators and included studies published up to 17 August 2021. For the systematic review, case reports, short communications and retrospective studies were included to ensure sufficient asymptomatic COVID-19 transmission data were reported. For the quantitative synthesis (meta-analysis), participant data from a collection of cohort studies focusing on groups of familial clusters, adults, children and health care workers were included. Inconsistency among studies was assessed using I
resultsThis study showed asymptomatic transmission among familial clusters, adults, children and health care workers of 15.72%, 29.48%, 24.09% and 0%, respectively. Overall, asymptomatic transmission was 24.51% (95% confidence interval [CI]: 14.38, 36.02) among all studied population groups, with a heterogeneity of I
conclusionsFor minimising the spread of COVID-19 within the community, this study found that following the screening of asymptomatic cases and their close contacts for chest CT scan (for symptomatic patients), even after negative nucleic acid testing, it is essential to perform a rigorous epidemiological history, early isolation, social distancing and an increased quarantine period (a minimum of 14-28 days). This systematic review and meta-analysis supports the notion of asymptomatic COVID-19 infection and person-to-person transmission and suggests that this is dependent on the varying viral incubation period among individuals. Children, especially those of school age (i.e. <18 years), need to be monitored carefully and follow mitigation strategies (e.g. social distancing, hand hygiene, wearing face masks) to prevent asymptomatic community transmission of COVID-19.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.