ArticleSexual medicine2022
Intensified Hyposensitization Is an Effective Treatment of Postorgasmic Illness Syndrome (POIS).
Article in Sexual medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 11 citations in OpenAlex.
- Data-Driven symptom clustering identifies four potential phenotypes of self-reported postorgasmic illness syndrome: findings from a large Chinese online survey.International journal of impotence research · 2026Article
- Post orgasmic illness syndrome: a review.International journal of impotence research · 2025Review
- Clinical characteristics, allergic response to autologous semen, and desensitization in patients with postorgasmic illness syndrome.Sexual medicine · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPostorgasmic illness syndrome (POIS) is an extremely rare urogenital disease which significantly and negatively impacts the functioning and sexual activity.
aimsA 34-year-old male presented with POIS symptoms and confirmed the allergic component of the POIS. Intensified immunotherapy with autologous semen was recommended.
methodsThe treatment lasted 14 months and included 20 visits. Modified and intensified subcutaneous immunotherapy in both forearms significantly shortened the therapy and improved the outcome, with high-tolerance and no adverse effects or hyperactive responses.
main outcome measureImprovement in POIS symptoms through the use of intensified immunotherapy with autologous semen.
resultsThe improvement was significant enough to allow for higher sexual activity, and gradual resumption of private and professional activity.
conclusionIntensified immunotherapy with autologous semen seems an effective and safe option for treating patients with suspected immune-allergenic POIS. To the best of our knowledge, this has been the first such intensive and effective allergen-specific immunotherapy of POIS. Wrotynska-Barczynska J, Swat. Swat E, Berger A, et al. Intensified Hyposensitization Is an Effective Treatment of Postorgasmic Illness Syndrome (POIS). Sex Med 2022;10:100474.
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