Evidence map›Paper›PMID 35038236›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Comment on: The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ.

Hanna S Schymik, Charlotte Dahlem, Ahmad Barghash, Alexandra K Kiemer

Open access · goldAbstract readComment
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Progression of mCell death discovery · 2024
    Review
  3. Article
  4. Article
  5. Exploring the impact of mFrontiers in immunology · 2024
    Review
  6. Macrophages in immunoregulation and therapeutics.Signal transduction and targeted therapy · 2023
    Review
  7. The Characterization and Differential Analysis of mAnimals : an open access journal from MDPI · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hanna S SchymikDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, Saarbruecken, 66123, Germany.ORCID 0000-0002-5384-9468
Charlotte DahlemDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, Saarbruecken, 66123, Germany.ORCID 0000-0001-9983-0802
Ahmad BarghashSchool of Electrical Engineering and Information Technology, German Jordanian University, Amman, 11180, Jordan.
Alexandra K KiemerDepartment of Pharmacy, Pharmaceutical Biology, Saarland University, Saarbruecken, 66123, Germany.ORCID 0000-0002-7224-9900
Saarland University · DEGerman Jordanian University · JO

Funding

Deutsche Forschungsgemeinschaft KI702
6 · The paper itself

Abstract

Recently, first insights into the regulation and the role of the RNA-binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti-inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages.

Indexed as

Macrophage ActivationPPAR gammaAnimalsHumansMacrophagesMiceRNA-Binding ProteinsIGF2BP2 protein, humanPPAR gammaRNA-Binding Proteinshuman macrophagesIFNγ Ι IGF2BP2LPSmacrophage polarizationmouse macrophagesspecies difference

Identifiers

PMID35038236
PMCPMC8922093
OpenAlexW4205208739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.