Evidence map›Paper›PMID 35038110›Full record

ArticleIrish journal of medical science2022

The cost of cancer care: how far would you go for a trial?

Orla M Fitzpatrick, Catherine Murphy, Erica Duignan, Keith Egan, Bryan T Hennessy, Liam Grogan, Adrian Murphy, Oscar S Breathnach, Jarushka Naidoo, Patrick G Morris

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Irish journal of medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Financial Toxicity in Cancer Clinical Trials: An Issue in Need of Clarity and Solutions.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Orla M FitzpatrickCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland. orlafitzpatrick@rcsi.com.ORCID http://orcid.org/0000-0002-2599-0966
Catherine MurphyCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Erica DuignanCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Keith EganCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Bryan T HennessyCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Liam GroganCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Adrian MurphyCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Oscar S BreathnachCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Jarushka NaidooCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Patrick G MorrisCancer Clinical Trials and Research Unit, Medical Oncology Department, Beaumont RCSI Cancer Centre, Beaumont Hospital, Dublin, Ireland.
Beaumont Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical trials are often considered the gold standard in cancer care. However, patients face barriers in trial participation including distances to cancer centres and personal costs including changing employment status, cost of medications, inpatient admissions, and parking tariffs.

aimOur aim was to compare the distances patients travelled for clinical trials compared to those receiving standard systemic anticancer therapy (SACT). We also investigated the additional costs associated with this.

methodsThis was a retrospective review of electronic patient medical records. The distance from the patients' home address to Beaumont was calculated as a one-way journey in kilometres. Patients attending for clinical trials were compared to those receiving standard of care SACT.

resultsA total of 271 patients receiving standard SACT over a 5-day period and 111 patients enrolled on 24 clinical trials were included. The median one-way distance travelled by patients enrolled in clinical trials was 41.4 km, compared to 14 km in those patients' receiving standard of care SACT. The median estimated cost was €13 vs €4.20 for those enrolled on clinical trials compared to those receiving standard of care treatment, respectively.

conclusionPatients enrolled on clinical trials often travel more than twice as far to receive their anti-cancer treatment compared to those receiving standard of care SACT and incur an increased cost of travel expenses.

Indexed as

ImmunotherapyNeoplasmsHospitalizationHumansRetrospective StudiesTravelClinical trialsDistanceExpenseOncology

Identifiers

PMID35038110
PMCPMC8761872
OpenAlexW4206559791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.