SynthesisSports medicine - open2022
The Effect of Load and Volume Autoregulation on Muscular Strength and Hypertrophy: A Systematic Review and Meta-Analysis.
Synthesis in Sports medicine - open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Relative effectiveness of different resistance training modalities on lower-body strength and explosive power: a systematic review and network meta-analysis.Frontiers in physiology · 2026Pooled it
- Preferred Reporting Items for Resistance Exercise Studies (PRIRES): A Checklist Developed Using an Umbrella Review of Systematic Reviews.Sports medicine - open · 2023Pooled it
- Influence of Resistance Training Proximity-to-Failure on Skeletal Muscle Hypertrophy: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Trial
- Intra-set rest preserves barbell velocity during a free-weight back squat exercise by shifting energy system contribution.Experimental physiology · 2026Article
- American College of Sports Medicine Position Stand. Resistance Training Prescription for Muscle Function, Hypertrophy, and Physical Performance in Healthy Adults: An Overview of Reviews.Medicine and science in sports and exercise · 2026 · on this mapReview
- Effect of velocity loss squat induced post-activation performance enhancement on lower limb explosive power in sprinters.Frontiers in physiology · 2026Article
- Conceptualizing a load and volume autoregulation integrated velocity model to minimize neuromuscular fatigue and maximize neuromuscular adaptations in resistance training.European journal of applied physiology · 2025Review
- Velocity-based training in mid- and late-stage rehabilitation after anterior cruciate ligament reconstruction: a narrative review and practical guidelines.BMJ open sport & exercise medicine · 2025Review
- The role of resistance exercise-induced local metabolic stress in mediating systemic health and functional adaptations: could condensed training volume unlock greater benefits beyond time efficiency?Frontiers in physiology · 2025Review
- Article
- Rate of Perceived Exertion Based on Repetitions in Reserve Versus Percentage of One-Repetition Maximum for Resistance Training Prescription in Cardiac Rehabilitation: A Pilot Study.Journal of cardiovascular development and disease · 2024Article
- The Importance of Recovery in Resistance Training Microcycle Construction.Journal of human kinetics · 2024Review
- A practical framework for the design of resistance exercise interventions in oncology research settings-a narrative review.Frontiers in sports and active living · 2024Review
- Integrating Deloading into Strength and Physique Sports Training Programmes: An International Delphi Consensus Approach.Sports medicine - open · 2023Article
- Exercise Training in Non-Hospitalized Patients with Post-COVID-19 Syndrome-A Narrative Review.Healthcare (Basel, Switzerland) · 2023Review
- Effects of Velocity-Based versus Percentage-Based Resistance Training on Explosive Neuromuscular Adaptations and Anaerobic Power in Sport-College Female Basketball Players.Healthcare (Basel, Switzerland) · 2023Article
- The Effect of Velocity Loss on Strength Development and Related Training Efficiency: A Dose-Response Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- Next steps to advance general physical activity recommendations towards physical exercise prescription: a narrative review.BMJ open sport & exercise medicine · 2023Review
- The effects of velocity-based versus percentage-based resistance training on athletic performances in sport-collegiate female basketball players.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAutoregulation has emerged as a potentially beneficial resistance training paradigm to individualize and optimize programming; however, compared to standardized prescription, the effects of autoregulated load and volume prescription on muscular strength and hypertrophy adaptations are unclear. Our objective was to compare the effect of autoregulated load prescription (repetitions in reserve-based rating of perceived exertion and velocity-based training) to standardized load prescription (percentage-based training) on chronic one-repetition maximum (1RM) strength and cross-sectional area (CSA) hypertrophy adaptations in resistance-trained individuals. We also aimed to investigate the effect of volume autoregulation with velocity loss thresholds ≤ 25% compared to > 25% on 1RM strength and CSA hypertrophy.
methodsThis review was performed in accordance with the PRISMA guidelines. A systematic search of MEDLINE, Embase, Scopus, and SPORTDiscus was conducted. Mean differences (MD), 95% confidence intervals (CI), and standardized mean differences (SMD) were calculated. Sub-analyses were performed as applicable.
resultsFifteen studies were included in the meta-analysis: six studies on load autoregulation and nine studies on volume autoregulation. No significant differences between autoregulated and standardized load prescription were demonstrated for 1RM strength (MD = 2.07, 95% CI - 0.32 to 4.46 kg, p = 0.09, SMD = 0.21). Velocity loss thresholds ≤ 25% demonstrated significantly greater 1RM strength (MD = 2.32, 95% CI 0.33 to 4.31 kg, p = 0.02, SMD = 0.23) and significantly lower CSA hypertrophy (MD = 0.61, 95% CI 0.05 to 1.16 cm
conclusionsCollectively, autoregulated and standardized load prescription produced similar improvements in strength. When sets and relative intensity were equated, velocity loss thresholds ≤ 25% were superior for promoting strength possibly by minimizing acute neuromuscular fatigue while maximizing chronic neuromuscular adaptations, whereas velocity loss thresholds > 20-25% were superior for promoting hypertrophy by accumulating greater relative volume. Protocol Registration The original protocol was prospectively registered (CRD42021240506) with the PROSPERO (International Prospective Register of Systematic Reviews).
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.