Evidence map›Paper›PMID 35038001›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2022

Association of the MAOA-uVNTR polymorphism with psychopathic traits may change from childhood to adolescence.

Tuana Kant, Emiko Koyama, Clement C Zai, Joseph H Beitchman, James L Kennedy

Abstract read
PubMed Publisher
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. International journal of molecular sciences · 2022
    Pooled it
  3. Article
  4. Heliyon · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tuana Kant *Institute of Medical Science, University of Toronto, Toronto, ON, Canada. tuana.kant@camh.ca.ORCID http://orcid.org/0000-0001-8152-5869
Emiko Koyama *Molecular Brain Science Department, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-4318-0585
Clement C ZaiInstitute of Medical Science, University of Toronto, Toronto, ON, Canada.
Joseph H BeitchmanInstitute of Medical Science, University of Toronto, Toronto, ON, Canada.
James L KennedyInstitute of Medical Science, University of Toronto, Toronto, ON, Canada. jim.kennedy@camh.ca.ORCID http://orcid.org/0000-0002-8733-3806
Centre for Addiction and Mental Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychopathic traits can lead to violence, making it a serious public health concern. Genetic factors contribute to the aetiology of psychopathy. We examined whether monoamine oxidase A (MAOA-uVNTR) was associated with psychopathic traits measured quantitatively from controls through clinically aggressive youth (n = 336). Subjects were sub-categorized into at or above, and below age 13 years. Results reveal that males below age 13 were more likely to display psychopathic traits with the MAOA long variant, whereas males above age 13 years were more likely to display with the short variant. This suggests that developmental factors may be crucial for understanding the role of the MAOA polymorphism in psychopathic traits in males.

Indexed as

Minisatellite RepeatsMonoamine OxidaseAdolescentAggressionAntisocial Personality DisorderChildGenotypeHumansMalePolymorphism, GeneticMonoamine Oxidasemonoamine oxidase A, humanAggressionCallous-unemotional traitsConduct disorderMAOA-VNTRMonoamine oxidase AYouth psychopathy

Identifiers

PMID35038001
OpenAlexW4205670456

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.