Evidence map›Paper›PMID 35037999›Full record

ArticleApplied microbiology and biotechnology2022

Screening and identification of B cell epitope of the nucleocapsid protein in SARS-CoV-2 using the monoclonal antibodies.

Yuanyuan Tian, Gaiping Zhang, Hongliang Liu, Peiyang Ding, Rui Jia, Jingming Zhou, Yumei Chen, Yanhua Qi, Jinran Du, Chao Liang and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yuanyuan TianSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Gaiping ZhangSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Hongliang LiuSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Peiyang DingSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Rui JiaSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Jingming ZhouSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Yumei ChenSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Yanhua QiSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Jinran DuSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Chao LiangSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Xifang ZhuSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China.
Aiping WangSchool of Life Sciences, Zhengzhou University, No. 100 Science Avenue, Zhengzhou, 450001, People's Republic of China. pingaw@126.com.ORCID http://orcid.org/0000-0003-1661-8174
Zhengzhou University · CN

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 2020 Fund ProjectInnovative Research Group Project of the National Natural Science Foundation of China grant number 32072944
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes the coronavirus disease (COVID-19). It is confirmed that nucleocapsid (N) protein is closely related to viral pathogenesis, modulation of host immune response, RNA transcription, and replication and virus packaging. Therefore, the N protein is a preponderant antigen target for virus detection. The codon-optimized N gene was designed according to the encoding characteristics of insect cells and inserted into pFastBac

Indexed as

COVID-19Nucleocapsid ProteinsAntibodies, MonoclonalAntibodies, ViralEpitope MappingEpitopes, B-LymphocyteHumansSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, MonoclonalAntibodies, ViralEpitopes, B-LymphocyteNucleocapsid ProteinsSpike Glycoprotein, CoronavirusB-cell epitopeMonoclonal antibodiesNucleocapsid proteinSARS-CoV-2

Identifiers

PMID35037999
PMCPMC8762450
OpenAlexW4206095448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.