ArticleDer Nervenarzt2022
[Spinal muscular atrophy].
Article in Der Nervenarzt, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- [Radicalization and "forced emigration": the dismissal and expulsion of neuroscientists and neuropsychiatrists from Vienna].Der Nervenarzt · 2022Review
- [The exclusion of "non-Aryan" scientists: universities, clinics and professional organizations].Der Nervenarzt · 2022Review
- ["… no reservations against the dismissals": the expulsion of neuroscientists from Berlin].Der Nervenarzt · 2022Review
- [Legalized deprivation of rights: on the legal construction of dismissal and expulsion under National Socialism].Der Nervenarzt · 2022Review
- [Late forced emigration without perspectives: Alfred Hauptmann and Adolf Wallenberg].Der Nervenarzt · 2022Review
- [Persecuted and forgotten? The neurologists Kurt Goldstein and Friedrich Heinrich Lewy].Der Nervenarzt · 2022Review
- ["Impossible to be part of this system any longer": the expulsion of neuroscientists from Frankfurt am Main (1933-1939)].Der Nervenarzt · 2022Review
- [Persecution, expulsion, annihilation. Neurologists in the NS era-For active remembrance].Der Nervenarzt · 2022Review
- ["We have to get rid of the Jews, either way": victims of violence among the neuroscientists].Der Nervenarzt · 2022Review
- [Context of the emigration of Jewish neurologists (1933-1939)].Der Nervenarzt · 2022Review
- [Disparate lives: Ludwig Guttmann and Robert Wartenberg].Der Nervenarzt · 2022Review
- [Persecution, expulsion and extermination of German-speaking neurologists during the NS era: attempt at an assessment].Der Nervenarzt · 2022Review
- ["There are no worthy life opportunities from a human, professional or scientific viewpoint": expelled neurologists outside the centers of German-speaking neuroscience].Der Nervenarzt · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spinal muscular atrophy (SMA) is an autosomal recessive disease caused by biallelic mutations in the SMN1 (survival motor neuron 1) gene on chromosome 5q13.2, which leads to a progressive degeneration of alpha motor neurons in the spinal cord and in motor nerve nuclei in the caudal brainstem. It is characterized by progressive proximally accentuated muscle weakness with loss of already acquired motor skills, areflexia and, depending on the phenotype, varying degrees of weakness of the respiratory and bulbar muscles, although the facial muscles and eye muscles are not affected. The previously purely symptom-oriented treatment has undergone a significant expansion since 2017 with the approval of three drugs (nusinersen, onasemnogene abeparvovec and risdiplam) that modify the course of the disease at the gene expression level and have led to a change in the natural disease course of SMA. The effect of these new forms of treatment can only be fully assessed in the coming years. New aspects and challenges in this context are discussed in this article.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.