ArticleSleep2022
Actigraphy-derived sleep health profiles and mortality in older men and women.
Article in Sleep, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- The prevalence and risk factors of sleep disturbances in community-dwelling older adults: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2025Pooled it
- Sleep patterns of Canadian women across the life course: A systematic review.Women's health (London, England)Pooled it
- Pediatric precision sleep network: a study protocol for identifying sleep signatures of mental health risk in peri-adolescents.BMC pediatrics · 2026Article
- Objective Sleep Measures and Cognition in Middle-Aged and Older Adults: A Cross-Sectional and Longitudinal Analysis in the ALBION Study.Medical sciences (Basel, Switzerland) · 2026Article
- Sleep Rhythmicity as a Core Domain of Multidimensional Sleep Health Associated with Cognitive Impairment in Older Men.Nature and science of sleep · 2026Article
- Tracking Cognitive Health With Wearables in Telerehabilitation Female Participants: Could Nighttime Sleep Measures Be Used as Sex-Specific Digital Endpoints?JMIR neurotechnology · 2026Article
- Circadian rhythm profiles derived from accelerometer measures of the sleep-wake cycle in two cohort studies.Nature communications · 2025Article
- Multidimensional sleep profiles via machine learning and risk of dementia and cardiovascular disease.Communications medicine · 2025Article
- Big data approaches for novel mechanistic insights on sleep and circadian rhythms: a workshop summary.Sleep · 2025Article
- The association between poor sleep health and Alzheimer's disease structural neuroimaging biomarkers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Sleep health profiles across six population-based cohorts and recommendations for validating clustering models.Sleep health · 2025Article
- Multidimensional Sleep Health: Definitions and Implications for Cardiometabolic Health: A Scientific Statement From the American Heart Association.Circulation. Cardiovascular quality and outcomes · 2025Review
- Five-Year Changes in 24-Hour Sleep-Wake Activity and Dementia Risk in Oldest Old Women.Neurology · 2025Article
- Article
- Accelerometry-assessed sleep clusters and obesity in adolescents and young adults: a longitudinal analysis in GINIplus/LISA birth cohorts.World journal of pediatrics : WJP · 2025Article
- The existing state of knowledge about sleep health in community-dwelling older persons - a scoping review.Annals of medicine · 2024Article
- Designing work for healthy sleep: A multidimensional, latent transition approach to employee sleep health.Journal of occupational health psychology · 2024Article
- Pioneering a multi-phase framework to harmonize self-reported sleep data across cohorts.Sleep · 2024Article
- Association of sleep fragmentation with general and abdominal obesity: a population-based longitudinal study.International journal of obesity (2005) · 2024Article
- Ten-Year Stability of an Insomnia Sleeper Phenotype and Its Association With Chronic Conditions.Psychosomatic medicine · 2024Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
STUDY
objectivesTo identify actigraphy sleep health profiles in older men (Osteoporotic Fractures in Men Study; N = 2640) and women (Study of Osteoporotic Fractures; N = 2430), and to determine whether profile predicts mortality.
methodsWe applied a novel and flexible clustering approach (Multiple Coalesced Generalized Hyperbolic mixture modeling) to identify sleep health profiles based on actigraphy midpoint timing, midpoint variability, sleep interval length, maintenance, and napping/inactivity. Adjusted Cox models were used to determine whether profile predicts time to all-cause mortality.
resultsWe identified similar profiles in men and women: High Sleep Propensity [HSP] (20% of women; 39% of men; high napping and high maintenance); Adequate Sleep [AS] (74% of women; 31% of men; typical actigraphy levels); and Inadequate Sleep [IS] (6% of women; 30% of men; low maintenance and late/variable midpoint). In women, IS was associated with increased mortality risk (Hazard Ratio [HR] = 1.59 for IS vs. AS; 1.75 for IS vs. HSP). In men, AS and IS were associated with increased mortality risk (1.19 for IS vs. HSP; 1.22 for AS vs. HSP).
conclusionsThese findings suggest several considerations for sleep-related interventions in older adults. Low maintenance with late/variable midpoint is associated with increased mortality risk and may constitute a specific target for sleep health interventions. High napping/inactivity co-occurs with high sleep maintenance in some older adults. Although high napping/inactivity is typically considered a risk factor for deleterious health outcomes, our findings suggest that it may not increase risk when it occurs in combination with high sleep maintenance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.