Evidence map›Paper›PMID 35037940›Full record

ArticleCerebral cortex (New York, N.Y. : 1991)2022

The ABCD Study: Brain Heterogeneity in Intelligence During a Neurodevelopmental Transition Stage.

Qi Zhao, Valerie Voon, Lingli Zhang, Chun Shen, Jie Zhang, Jianfeng Feng

Open access · bronzeAbstract read
In one paragraph

Article in Cerebral cortex (New York, N.Y. : 1991), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  8. Longitudinal Sex-at-Birth and Age Analyses of Cortical Structure in the ABCD Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  9. Cortical Thickness Differences in Autistic Children With and Without Intellectual Disability.Autism research : official journal of the International Society for Autism Research · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Qi ZhaoSchool of Mathematical Sciences, Fudan University, Shanghai 200433, PR China.ORCID 0000-0003-1716-141X
Valerie VoonDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0SZ, UK.
Lingli ZhangDevelopmental and Behavioral Pediatric & Child Primary Care Department, Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, PR China.
Chun ShenInstitute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai 200433, PR China.
Jie ZhangInstitute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai 200433, PR China.
Jianfeng FengInstitute of Science and Technology for Brain Inspired Intelligence, Fudan University, Shanghai 200433, PR China.
Fudan University · CNShanghai Jiao Tong University · CNUniversity of Cambridge · GB

Funding

Medical Research Council MR/P008747/1
6 · The paper itself

Abstract

A complex curvilinear relationship exists between intelligence and age during the neurodevelopment of cortical thickness. To parse out a more fine-grained relationship between intelligence and cortical thickness and surface area, we used a large-scale data set focusing on a critical transition juncture in neurodevelopment in preadolescence. Cortical thickness was derived from T1-weighted structural magnetic resonance images of a large sample of 9- and 11-year-old children from the Adolescent Brain Cognitive Development study. The NIH Toolbox Cognition Battery composite scores, which included fluid, crystallized, and total scores, were used to assess intelligence. Using a double generalized linear model, we assessed the independent association between the mean and dispersion of cortical thickness/surface area and intelligence. Higher intelligence in preadolescents was associated with higher mean cortical thickness in orbitofrontal and primary sensory cortices but with lower thickness in the dorsolateral and medial prefrontal cortex and particularly in the rostral anterior cingulate. The rostral anterior cingulate findings were particularly evident across all subscales of intelligence. Higher intelligence was also associated with greater interindividual similarity in the rostral cingulate. Intelligence during this key transition juncture in preadolescence appears to reflect a dissociation between the cortical development of basic cognitive processes and higher-order executive and motivational processes.

Indexed as

BrainIntelligenceAdolescentBrain MappingCerebral CortexChildCognitionHumansMagnetic Resonance Imagingadolescencecognitive processcortical thicknessintelligencesurface area

Identifiers

PMID35037940
PMCPMC9290553
OpenAlexW4205934080

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.