SynthesisDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2022
Electrolyte disturbances after bowel preparation for colonoscopy: Systematic review and meta-analysis.
Synthesis in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06313242 (Evaluation of Different Bowel Preparations in Magnetically Controlled Capsule Endoscopy), which is not on this map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Different Bowel Preparations in Magnetically Controlled Capsule Endoscopy: a Randomized Controlled Study
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Serious adverse events associated with bowel preparation for colonoscopy in Japan: Systematic review.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Pooled it
- The Influence of Mechanical Bowel Preparation on Volatile Organic Compounds for the Detection of Gastrointestinal Disease-A Systematic Review.Sensors (Basel, Switzerland) · 2023Pooled it
- Efficacy and safety of sodium phosphate powder for bowel cleansing in patients aged 50-70 years: a randomised, multicentre, single-blind trial.BMC gastroenterology · 2026Trial
- Encapsulated faecal microbiota transfer in young women with anorexia nervosa: an open-label feasibility pilot trial.Nature communications · 2025Trial
- Effects of oral carbohydrate loading in patients scheduled for painless bidirectional endoscopy: a prospective randomized controlled trial.Langenbeck's archives of surgery · 2024Trial
- Discretionary Versus Routine Intravenous Fluids for Ambulatory Gastrointestinal Endoscopies: A Cohort Study Following Hurricane Helene.Digestive diseases and sciences · 2026Article
- Outcomes of Screening Colonoscopy in Older Adults: A Large Propensity-Matched Real-World Cohort Study.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Rates of hypoglycemia and electrolyte abnormalities in children presenting for endoscopy in a tertiary hospital.Journal of pediatric gastroenterology and nutrition · 2026Article
- Effectiveness and safety of screening colonoscopy in adults aged 75 years and older: a retrospective cohort study from Korea.Clinical endoscopy · 2026Article
- Prebiotics and SCFA Alleviate Parkinson's-Related Constipation: Results from a Randomized Controlled Trial.Neurology and therapy · 2026Article
- Patient-reported outcomes and measures applied in individuals undergoing colonoscopy surveillance for colorectal cancer: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Acute severe hyperphosphatemia and secondary hypocalcemia after phosphate enema administration in a constipated post-trauma patient recovering from pelvic surgery: a case report.Journal of surgical case reports · 2026Article
- Review
- Feasibility and tolerability of reduced-volume oral sulfate solution combined with elobixibat for bowel preparation before colonoscopy: a single-center pilot study.Gastroenterology report · 2026Article
- The silent potassium avalanche: unchecking preoperative hypokalemia leading to perioperative cardiac arrest in an insulin-treated diabetic patient undergoing a Whipple procedure: a case report.BMC anesthesiology · 2025Article
- Balancing safety and effectiveness in colonoscopy for older adults: a narrative review.Intestinal research · 2025Review
- Article
- Risk Factors Asscociated with Hypokalemia during Postanesthesia Recovery and Its Impact on Outcomes in Gynecological Patients: A Propensity Score Matching Study.Current medical science · 2024Article
- Emerging space for non-polyethene-glycol bowel preparations in inflammatory bowel disease-related colonoscopy: Veering toward better adherence and palatability.World journal of gastroenterology · 2023Article
- Comparison of MiraLAX and magnesium citrate for bowel preparation at CT colonography.Abdominal radiology (New York) · 2023Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND STUDY
aimsWe conducted a systematic review and meta-analysis of population-based studies to explore pooled prevalence and magnitude of electrolyte changes after bowel preparation for colonoscopy based on the most recent guidelines. PATIENTS AND
methodsPubMed and Cochrane were queried for population-based studies examining changes in electrolyte values after bowel preparation, published by July 1, 2021. We report prevalences of serum hypokalemia, hyponatremia, hyperphosphatemia, and hypocalcemia after bowel preparation and changes in mean electrolyte values after vs. before bowel preparation using sodium phosphate (NaP) and polyethylene glycol (PEG).
resultsThirteen studies met the inclusion criteria; 2386 unique patients were included. Overall, hypokalemia was found in 17.2% (95% CI 6.7, 30.9) in the NaP group vs. 4.8% (95% CI 0.27, 13.02) in the PEG group. The magnitude of potassium decrease after NaP bowel preparation was significantly increased compared to PEG (mean difference -0.38; 95% CI -0.49 to -0.27, P < 0.001). No study reported on major complications.
conclusionsHypokalemia was found in 17.2% of patients after bowel preparation with NaP and in 4.8% of patients with PEG, a finding that is clinically relevant with respect to choosing the type of bowel preparation. The magnitude of the potassium decrease after NaP was significantly higher compared to PEG. These data provide the evidence that supports the recommendation of the European Society of Gastrointestinal Endoscopy against routine use of NaP for bowel preparation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.