ArticleThe Lancet regional health. Western Pacific2022
Hypertension Defined by 2017 ACC/AHA Guideline, Ideal Cardiovascular Health Metrics, and Risk of Cardiovascular Disease: A Nationwide Prospective Cohort Study.
Article in The Lancet regional health. Western Pacific, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Associations of Urban Built Environment with Cardiovascular Risks and Mortality: a Systematic Review.Journal of urban health : bulletin of the New York Academy of Medicine · 2023Pooled it
- Epigenetic regulation in type II diabetes: linking molecular mechanisms to clinical management.Journal of diabetes and metabolic disorders · 2026Review
- Outcome of children with fusion anomalies of the kidney: a single center experience from North India.International urology and nephrology · 2026Article
- Weekend warriors, physical activity pattern and all-cause mortality: a prospective study of 150,145 Mexican adults with and without hypertension.BMC public health · 2025Article
- Microvascular Health as a Key Determinant of Organismal Aging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Hypertension burden and associated risk factors among people from the slums in a developing country: evidence from the COMBAT-CVD study.Journal of human hypertension · 2025Article
- Quantifying the association of Life's Crucial 9 with cardiovascular diseases among elderly hypertensive patients managed in primary care settings.Population health metrics · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- Chinese Guidelines for the Prevention and Treatment of Hypertension (2024 revision).Journal of geriatric cardiology : JGC · 2025Article
- Digital-Based Nutrition Interventions Employing the Dietary Approaches to Stop Hypertension (DASH) Diet: A Systematic Scoping Review.International journal of hypertension · 2025Review
- Development and validation of a nomogram model for predicting the risk of hypertension in Bangladesh.Heliyon · 2024Article
- Cardiovascular health metrics and all-cause mortality in osteoarthritis, inflammatory arthritis, and unclassified arthritis patients: a national prospective cohort study.Arthritis research & therapy · 2024Article
- Missed opportunities for hypertension screening of older people in the Philippines: cross-sectional analysis of nationally representative individual-level data.The Lancet regional health. Western Pacific · 2024Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- Efficacy and safety of olmesartan medoxomil‑amlodipine besylate tablets (SevikarExperimental and therapeutic medicine · 2024Article
- Moderating role of functional/ mobility limitations in the association between sleep problems and hypertension among middle-aged and older adults in India.Preventive medicine reports · 2024Article
- Ideal cardiovascular health metrics have better identification of arthritis.BMC public health · 2024Article
- Efficacy and safety of olmesartan medoxomil-amlodipine besylate tablet in Chinese patients with essential hypertension: A prospective, single-arm, multi-center, real-world study.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Cardiovascular Toxicities of Radiation Therapy and Recommended Screening and Surveillance.Journal of cardiovascular development and disease · 2023Review
- Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association.Circulation · 2023Review
Corrections and comments
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Authors and funding
42 authors at 20 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe updated definition of hypertension by the American College of Cardiology (ACC) and the American Heart Association (AHA) is an important paradigm shift and has lead to extensive discussion. We aimed to examine the association between the updated blood pressure (BP) categories and the risk of cardiovascular diseases (CVDs) with potential modifications from other cardiovascular health metrics (CVHMs).
methodsThis prospective study included 91,204 participants ≥40 years recruited from 20 community sites across mainland China. Participants were followed up during 2010-2016 for CVD events including nonfatal myocardial infarction, stroke, heart failure, and cardiovascular death. BP categories were defined according to the 2017 ACC/AHA guideline and CVHMs included smoking, physical activity, diet, body-mass index, total cholesterol, and fasting glucose.
findingsOverall, 1,985 major CVD events occurred during a mean follow-up of 3.7 years. Having more ideal CVHMs significantly reduced the risk of CVD events in both stage 1 and stage 2 hypertension. Compared with participants without hypertension, participants having ≥4 ideal CVHMs were no longer associated with an increased CVD risk in stage 1 hypertension (HR=1·04; 95% CI=0·83-1·31), but less so in stage 2 hypertension (HR=1·90, 95% CI=1·70-2·13). Such pattern of association was more evident in participants aged <60 years (
interpretationStage 1 hypertension defined by the ACC/AHA identifies individuals at increased CVD risk, which can be attenuated by achieving more preferable cardiovascular health, especially in adults aged <60 years.
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