Evidence map›Paper›PMID 35036954›Full record

ArticleSTAR protocols2022

A protocol to evaluate epithelial regeneration after inducing cell loss in zebrafish larvae.

Oscar E Ruiz, Krystin M Samms, George T Eisenhoffer

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in STAR protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Oscar E RuizDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Krystin M SammsDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
George T EisenhofferDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
The University of Texas MD Anderson Cancer Center · US

Funding

Regulation of Cell Turnover During Epithelial Tissue HomeostasisR01GM124043 · NIGMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI EISENHOFFER, GEORGE THOMAS · 2018 to 2022
$2.0M
NIGMS NIH HHS R01 GM124043
6 · The paper itself

Abstract

Epithelial tissues sustain barrier function by removing and replacing aberrant or unfit cells. Here, we describe approaches to evaluate epithelial restorative capacity after inducing cell loss in zebrafish larvae. We provide details to quantify morphological changes to the tail fin epithelium after cell loss, and instructions to interrogate changes in gene expression and proliferation associated with replacement of the lost cells. Together, this approach establishes an

Indexed as

RegenerationZebrafishAnimalsEpitheliumLarvaCell BiologyDevelopmental biologyIn Situ HybridizationMicroscopyModel Organisms

Identifiers

PMID35036954
PMCPMC8749296
OpenAlexW4206707052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.