Evidence map›Paper›PMID 35036870›Full record

ArticleiScience2022

An adipose lncRAP2-Igf2bp2 complex enhances adipogenesis and energy expenditure by stabilizing target mRNAs.

Juan R Alvarez-Dominguez, Sally Winther, Jacob B Hansen, Harvey F Lodish, Marko Knoll

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Unraveling Obesity: A Five-Year Integrative Review of Transcriptomic Data.International journal of molecular sciences · 2025
    Review
  2. IGF2BP2: an mCellular & molecular biology letters · 2025
    Review
  3. IMPlications of IMP2 in RNA Biology and Disease.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Rna MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. LncRNA-Mediated Adipogenesis in Different Adipocytes.International journal of molecular sciences · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Juan R Alvarez-DominguezWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA, 02142, USA.
Sally WintherDepartment of Biology, University of Copenhagen, Universitetsparken 13, DK2100, Copenhagen, Denmark.
Jacob B HansenDepartment of Biology, University of Copenhagen, Universitetsparken 13, DK2100, Copenhagen, Denmark.
Harvey F LodishWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA, 02142, USA.
Marko KnollWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA, 02142, USA.
University of Copenhagen · DKWhitehead Institute for Biomedical Research · USHelmholtz Zentrum München · DE

Funding

MicroRNAs and hematopoietic differentiationR01DK068348 · NIDDK · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI LODISH, HARVEY F · 2004 to 2019
$8.3M
Lincs and miRs that regulate brown fat formation and functionR01DK047618 · NIDDK · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI LODISH, HARVEY F · 1994 to 2016
$6.3M
ADIPOCYTE PROTEIN SECRETION AND INSULIN ACTIONR37DK047618 · NIDDK · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI LODISH, HARVEY F · 1998 to 2007
$4.8M
MicroRNAs and hematopoietic differentiationR56DK068348 · NIDDK · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI BARTEL, DAVID P, LODISH, HARVEY F · 2010 to 2010
$230k
NIDDK NIH HHS R01 DK047618NIDDK NIH HHS R01 DK068348NIDDK NIH HHS R37 DK047618NIDDK NIH HHS R56 DK068348
6 · The paper itself

Abstract

lncRAP2 is a conserved cytoplasmic lncRNA enriched in adipose tissue and required for adipogenesis. Using purification and

Indexed as

Biological sciencesMolecular biologyMolecular physiologyOmics

Identifiers

PMID35036870
PMCPMC8749451
OpenAlexW4200190660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.