ArticleACS omega2022
Diffusion-Controlled Crystallization of Calcium Phosphate in a Hydrogel toward a Homogeneous Octacalcium Phosphate/Agarose Composite.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 23 citations in OpenAlex.
- Octacalcium Phosphate/Calcium Citrate/Methacrylated Gelatin Composites: Optimization of Photo-Crosslinking Conditions and Osteogenic Potential Evaluation.International journal of molecular sciences · 2025Article
- Characterization of MSC Growth, Differentiation, and EV Production in CNF Hydrogels Under Static and Dynamic Cultures in Hypoxic and Normoxic Conditions.Bioengineering (Basel, Switzerland) · 2024Article
- Mineralized Microgels via Electrohydrodynamic Atomization: Optimization and In Vitro Model for Dentin-Pulp Complex.Gels (Basel, Switzerland) · 2023Article
- Diffusion-Limited Processes in Hydrogels with Chosen Applications from Drug Delivery to Electronic Components.Molecules (Basel, Switzerland) · 2023Review
- Bioinspired Control of Calcium Phosphate Liesegang Patterns Using Anionic Polyelectrolytes.Langmuir : the ACS journal of surfaces and colloids · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diffusion-controlled crystallization in a hydrogel has been investigated to synthesize organic/inorganic hybrid composites and obtain a fundamental understanding of the detailed mechanism of biomineralization. Although calcium phosphate/hydrogel composites have been intensively studied and developed for the application of bone substitutes, the synthesis of homogeneous and integrated composites remains challenging. In this work, diffusion-controlled systems were optimized by manipulating the calcium ion flux at the interface, concentration gradient, and diffusion coefficient to synthesize homogeneous octacalcium phosphate/hydrogel composites with respect to the crystal morphology and density. The ion flux and local pH play an important role in determining the morphology, density, and phase of the crystals. This study suggests a model system that can reveal the relation between local conditions and the resulting crystal phase in diffusion-limited systems and provides a synthetic method for homogeneously organized organic/inorganic composites.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.