Evidence map›Paper›PMID 35036636›Full record

ArticleAdvances in radiation oncology

Positron Emission Tomography-Derived Metrics Predict the Probability of Local Relapse After Oligometastasis-Directed Ablative Radiation Therapy.

Carlo Greco, Oriol Pares, Nuno Pimentel, Vasco Louro, Javier Morales, Beatriz Nunes, Inês Antunes, Ana Luisa Vasconcelos, Justyna Kociolek, Joana Castanheira and 7 more

Open access · goldAbstract read
In one paragraph

Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Joint EANM-SNMMI guideline on the role of 2-[European journal of nuclear medicine and molecular imaging · 2024
    Guideline
  2. Prognostic Role ofCancers · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Lesion Dosimetry for [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 2 countries.

Carlo GrecoDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Oriol ParesDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Nuno PimentelDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Vasco LouroDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Javier MoralesDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Beatriz NunesDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Inês AntunesDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Ana Luisa VasconcelosDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Justyna KociolekDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Joana CastanheiraDepartment of Nuclear Medicine-Radiopharmacology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Carla OliveiraDepartment of Nuclear Medicine-Radiopharmacology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Angelo SilvaDepartment of Nuclear Medicine-Radiopharmacology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Sofia VazDepartment of Nuclear Medicine-Radiopharmacology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Francisco OliveiraDepartment of Nuclear Medicine-Radiopharmacology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Eunice CarrasquinhaComputational Clinical Imaging Group, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Durval CostaDepartment of Nuclear Medicine-Radiopharmacology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Zvi FuksDepartment of Radiation Oncology, Champalimaud Centre for the Unknown, Lisbon, Portugal.
Champalimaud Foundation · PT

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeEarly positron emission tomography-derived metrics post-oligometastasis radioablation may predict impending local relapses (LRs), providing a basis for a timely ablation. METHODS AND MATERIALS: Positron emission tomography data of 623 lesions treated with either 24 Gy single-dose radiation therapy (SDRT) (n = 475) or 3 ×  9 Gy stereotactic body radiation therapy (SBRT) (n = 148) were analyzed in a training data set (n = 246) to obtain optimal cutoffs for pretreatment maximum standardized uptake value (SUV

resultsAt a median of 21.7 months, 91 lesions developed LRs: 39 of 475 (8.2%) after SDRT and 52 of 148 (35.1%) after SBRT. The optimal cutoff values were 12 for SUV

conclusionsThe SBRT dual-adverse SUV

Identifiers

PMID35036636
PMCPMC8752878
OpenAlexW4200162312

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.