Evidence map›Paper›PMID 35036445›Full record

Trial reportBioMed research international2022

Association of lncRNA PVT1 Gene Polymorphisms with the Risk of Essential Hypertension in Chinese Population.

Rong Li, Xia Yu, Yang Chen, Mulun Xiao, Meiling Zuo, Yuanlin Xie, Zhousheng Yang, Dabin Kuang

Open access · hybridAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Rong LiInstitute of Pharmacy & Pharmacology and the Second Affiliated Hospital, University of South China, Hengyang 421001, China.
Xia YuInstitute of Pharmacy & Pharmacology and the Second Affiliated Hospital, University of South China, Hengyang 421001, China.
Yang ChenInstitute of Pharmacy & Pharmacology and the Second Affiliated Hospital, University of South China, Hengyang 421001, China.
Mulun XiaoDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China.
Meiling ZuoThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, Hunan 410006, China.
Yuanlin XieThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, Hunan 410006, China.
Zhousheng YangDepartment of Pharmacy, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.ORCID https://orcid.org/0000-0002-3465-7268
Dabin KuangThe Affiliated Changsha Hospital of Hunan Normal University, Changsha, Hunan 410006, China.ORCID https://orcid.org/0000-0002-6240-038X
Hunan Normal University · CNUniversity of South China · CNFirst Affiliated Hospital of Zhengzhou University · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular dysfunction and hyperlipidemia are essential risk factors contributing to essential hypertension (EH). The plasmacytoma variant translocation 1 (PVT1) is involved in modulating angiogenesis in tumor tissues and plays an important role in fat differentiation in the progress of obesity. Therefore, we selected two tagSNPs of PVT1 (rs10956390 and rs80177647) to investigate whether they are contributing to the risk of hypertension in Chinese patients. In total, 524 adult patients with EH and 439 matched healthy controls were enrolled for two central of China.

Indexed as

Polymorphism, Single NucleotideAdultAsian PeopleChinaEssential HypertensionFemaleHumansMaleMiddle AgedRisk FactorsRNA, Long NoncodingPVT1 long-non-coding RNA, humanRNA, Long Noncoding

Identifiers

PMID35036445
PMCPMC8758273
OpenAlexW4206243218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.