Evidence map›Paper›PMID 35036435›Full record

ArticleBioMed research international2022

NF-

Qiuxiang Chen, Xiaojing Du, Sunkuan Hu, Qingke Huang

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Predictors of immunotherapy response in gastric cancer: the role of the tumor microenvironment and integrative predictive models.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Targeting one-carbon metabolism for cancer immunotherapy.Clinical and translational medicine · 2024
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Qiuxiang ChenDepartment of Ultrasonic Imaging, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.ORCID https://orcid.org/0000-0001-8231-8757
Xiaojing DuDepartment of Gastroenterology, Minhang Hospital, Fudan University, 170 Xinsong Road, Shanghai 201199, China.ORCID https://orcid.org/0000-0001-8228-5086
Sunkuan HuDepartment of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.ORCID https://orcid.org/0000-0003-2696-0723
Qingke HuangDepartment of Gastroenterology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.ORCID https://orcid.org/0000-0003-4933-3693
Wenzhou Medical University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSufficient evidence indicated the crucial role of NF-

methodsTCGA, hTFtarget, and MSigDB databases were employed to identify NF-

resultsWe used 27 NFMGs to conduct an unsupervised clustering on GC samples and classified them into two clusters. Cluster 1 was characterized by high active metabolism, tumor mutant burden, and microsatellite instability, while cluster 2 was featured with high immune infiltration. Compared to cluster 2, cluster 1 had a better prognosis and higher response to immunotherapy. In addition, we constructed a 12-NFMG (

conclusionOur data suggested that GC subtypes classified by NFMGs may effectively guide prognosis and immunotherapy. Further study of these NFMGs will deepen our understanding of NF-

Indexed as

Stomach NeoplasmsBiomarkers, TumorGene Expression Regulation, NeoplasticHumansNeoplasm ProteinsNF-kappa BPrognosisTumor MicroenvironmentBiomarkers, TumorNeoplasm ProteinsNF-kappa B

Identifiers

PMID35036435
PMCPMC8753254
OpenAlexW4205268136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.