Evidence map›Paper›PMID 35036306›Full record

ArticleRespiratory medicine case reports2022

Spirometry testing for extracorporeal membrane oxygenation (ECMO) bridge to transplant patients.

Irina Timofte, Montserrat Diaz-Abad, Fahid Alghanim, Jordan Assadi, Christine Lau, Ronson Madathil, Bartley Griffith, Daniel Herr, Aldo Iacono, Stella Hines

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Irina TimofteDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Montserrat Diaz-AbadDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Fahid AlghanimDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Jordan AssadiUniversity of Maryland Baltimore Washington Medical Center, 301 Hospital Dr, Glen Burnie, MD, 21061, United States.
Christine LauDepartment of Surgery, University of Maryland Medical Center, Baltimore, MD, United States.
Ronson MadathilDepartment of Surgery, University of Maryland Medical Center, Baltimore, MD, United States.
Bartley GriffithDepartment of Surgery, University of Maryland Medical Center, Baltimore, MD, United States.
Daniel HerrDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Aldo IaconoDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Stella HinesDepartment of Medicine, University of Texas Southwestern Medical Center, Dallas, TX, United States.
University of Maryland, Baltimore · USThe University of Texas Southwestern Medical Center · US

Funding

Pharmacokinetics (PK) and Pharmacodynamics (PD) Characterization of mTOR Inhibitors in Older AdultsU01AG081450 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI Allison Dunn, Yan Shu · 2024 to 2026
$1.8M
NIA NIH HHS U01 AG081450
6 · The paper itself

Abstract

purposeECMO can provide a bridge to transplantation and improve survival for patients with advanced lung disease. Although pulmonary function testing (PFT) is an important component of the lung allocation score (LAS), it is not always feasible on patients requiring ECMO. While generally safe, PFT testing has contraindications and is not recommended in unstable patients. Currently there are no recommendations regarding the performance of spirometry in ECMO patients. STUDY

designand Methods: We reviewed data on five patients with advanced lung disease requiring ECMO-bridge to transplant. After careful consideration of the theoretical physiologic risks associated with forced expiratory maneuvers, bedside spirometry was performed in order to update the patients' LAS.

resultsAll patients successfully completed three forced expiratory maneuvers in the seated position with a bedside spirometer. Vital signs and ECMO flow were stable during testing and without complication. In 2 patients who had both a LAS pre and post spirometry, the LAS increased by 3-5 points.

conclusionSpirometry results are pivotal to organ allocation under current organ sharing protocols. This case series demonstrates that bedside spirometry testing may be performed safely in patients on ECMO awaiting lung transplantation without appreciable side effects, leading to a more accurate LAS score.

Indexed as

Extra-corporeal membrane oxygenation (ECMO)Lung allocation scoreLung transplantationPulmonary function testSpirometry

Identifiers

PMID35036306
PMCPMC8749276
OpenAlexW4205263795

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