Evidence map›Paper›PMID 35036185›Full record

ArticleCureus2021

Could Fahr's Syndrome Have More Than One Simultaneous Etiology?

Gabriele Palu, Samia T Moraes, Gabriela Romaniello, Luis O Zatorre, Luiza K Seixas, Rafael Miyazima, Gustavo Lenci Marques

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gabriele PaluInternal Medicine Department, Federal University of Parana, Curitiba, BRA.
Samia T MoraesInternal Medicine Department, Federal University of Parana, Curitiba, BRA.
Gabriela RomanielloInternal Medicine Department, Federal University of Parana, Curitiba, BRA.
Luis O ZatorreInternal Medicine Department, Federal University of Parana, Curitiba, BRA.
Luiza K SeixasInternal Medicine Department, Federal University of Parana, Curitiba, BRA.
Rafael MiyazimaInternal Medicine Department, Federal University of Parana, Curitiba, BRA.
Gustavo Lenci MarquesInternal Medicine Department, Federal University of Parana, Curitiba, BRA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fahr's syndrome is a rare, genetically dominant, inherited, neurological disorder characterized by abnormal deposits of calcium in the basal ganglia and the cerebral cortex. Symptoms include motor dysfunction, dementia, headache, spastic paralysis, abnormal ocular findings and seizures. Hypoparathyroidism is the most common endocrine disorder related to this syndrome, however, there are other metabolic, infectious and genetic causes. This is a case report of a Fahr's syndrome patient presenting a three-month history of self-limited partial epileptic seizures. His cranial CT had bilateral symmetrical calcifications of the basal ganglia, subcortical tissue and dentate nucleus whereas his laboratory findings were compatible with hypoparathyroidism.

Indexed as

cerebral calcificationsfahr’s disease or fahr’s syndromehypoparathyroidismnew-onset seizuresecondary hypocalcemia

Identifiers

PMID35036185
PMCPMC8752340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.