Evidence map›Paper›PMID 35036174›Full record

ArticlePeerJ2021

Differential expression profiles of microRNAs in musk gland of unmated and mated forest musk deer (

Hang Jie, Zhongxian Xu, Jian Gao, Feng Li, Yinglian Chen, Dejun Zeng, Guijun Zhao, Diyan Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hang Jie *Chongqing Institute of Medicinal Plant Cultivation, Bio-resource Research and Utilization joint key laboratory of Sichuan and Chongqing, Nanchuan, Chongqing, China.
Zhongxian Xu *Sichuan Agricultural University, Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Chengdu, Sichuan, China.
Jian GaoSichuan Agricultural University, Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Chengdu, Sichuan, China.
Feng LiSichuan Agricultural University, Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Chengdu, Sichuan, China.
Yinglian ChenChongqing Institute of Medicinal Plant Cultivation, Bio-resource Research and Utilization joint key laboratory of Sichuan and Chongqing, Nanchuan, Chongqing, China.
Dejun ZengChongqing Institute of Medicinal Plant Cultivation, Bio-resource Research and Utilization joint key laboratory of Sichuan and Chongqing, Nanchuan, Chongqing, China.
Guijun ZhaoChongqing Institute of Medicinal Plant Cultivation, Bio-resource Research and Utilization joint key laboratory of Sichuan and Chongqing, Nanchuan, Chongqing, China.
Diyan LiSichuan Agricultural University, Institute of Animal Genetics and Breeding, College of Animal Science and Technology, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe formation of musk is a complex biophysical and biochemical process that change with the rut of male forest musk deer. We have reported that the mating status of male forest musk deer might result to the variations of chemical composition and microbiota of musk and its yields. Critical roles for microRNAs (miRNAs) of multi-tissues were profiled in our previous study; however, the role for miRNAs of the musk gland remains unclear in this species.

methodsIn this study, we used Illumina deep sequencing technology to sequence the small RNA transcriptome of unmated male (UM) and mated male (UM) of Chinese forest musk deer.

resultsWe identified 1,652 known miRNAs and 45 novel miRNAs, of which there were 174 differentially expressed miRNAs between UM and MM. chi-miR-21-5p, ipu-miR-99b and bta-miR-26a were up-regulated in UM among the 10 most differentially expressed miRNAs. Functional enrichment of the target genes showed that monosaccharide biosynthetic process, protein targeting, cellular protein catabolic process enriched higher in MM. Meanwhile, structural molecule activity, secretion by cell, regulated exocytosis and circulatory system process enriched more in UM, hinting that the formation of musk in UM was mediated by target genes related to exocytosis. The miRNA-mRNA pairs such as miR-21:

Indexed as

Expression profileMating statusMicroRNAMusk deerMusk gland

Identifiers

PMID35036174
PMCPMC8710055

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