Evidence map›Paper›PMID 35036029›Full record

ArticleImmune network2021

NLRC4 Inflammasome-Mediated Regulation of Eosinophilic Functions.

Ilgin Akkaya, Ece Oylumlu, Irem Ozel, Goksu Uzel, Lubeyne Durmus, Ceren Ciraci

Abstract read
In one paragraph

Article in Immune network, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. IL-18 biology in severe asthma.Frontiers in medicine · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ilgin AkkayaDepartment of Molecular Biology and Genetics, Istanbul Technical University, Istanbul 34469, Turkey.ORCID https://orcid.org/0000-0003-1550-8221
Ece OylumluDepartment of Molecular Biology and Genetics, Istanbul Technical University, Istanbul 34469, Turkey.ORCID https://orcid.org/0000-0003-4234-9086
Irem OzelDepartment of Molecular Biology and Genetics, Istanbul Technical University, Istanbul 34469, Turkey.ORCID https://orcid.org/0000-0002-7007-9928
Goksu UzelDepartment of Molecular Biology and Genetics, Istanbul Technical University, Istanbul 34469, Turkey.ORCID https://orcid.org/0000-0002-2718-6197
Lubeyne DurmusDepartment of Molecular Biology and Genetics, Istanbul Technical University, Istanbul 34469, Turkey.ORCID https://orcid.org/0000-0002-6648-4197
Ceren CiraciDepartment of Molecular Biology and Genetics, Istanbul Technical University, Istanbul 34469, Turkey.ORCID https://orcid.org/0000-0003-2162-0930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophils play critical roles in the maintenance of homeostasis in innate and adaptive immunity. Although primarily known for their roles in parasitic infections and the development of Th2 cell responses, eosinophils also play complex roles in other immune responses ranging from anti-inflammation to defense against viral and bacterial infections. However, the contributions of pattern recognition receptors in general, and NOD-like receptors (NLRs) in particular, to eosinophil involvement in these immune responses remain relatively underappreciated. Our

Indexed as

EosinophilInflammasomeNLR proteinsPattern recognition receptor

Identifiers

PMID35036029
PMCPMC8733190

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.