Evidence map›Paper›PMID 35035943›Full record

ArticleClinical kidney journal2022

Peritoneal dialysis-first initiative in India: a cost-effectiveness analysis.

Dharna Gupta, Gaurav Jyani, Raja Ramachandran, Pankaj Bahuguna, Mohammed Ameel, Bharat Bhushan Dahiya, Harbir Singh Kohli, Shankar Prinja, Vivekanand Jha

Abstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Review
  3. Cumulative blood pressure exposure and cognition: the potential mediating role of brain volume.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. International equity in access to home dialysis.Current opinion in nephrology and hypertension · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dharna GuptaDepartment of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Gaurav JyaniDepartment of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0003-3787-2446
Raja RamachandranDepartment of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Pankaj BahugunaDepartment of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Mohammed AmeelNational Health Systems Resource Centre, Ministry of Health and Family Welfare, New Delhi, India.
Bharat Bhushan DahiyaNational Health Systems Resource Centre, Ministry of Health and Family Welfare, New Delhi, India.
Harbir Singh KohliDepartment of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Shankar PrinjaDepartment of Community Medicine and School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vivekanand JhaThe George Institute of Global Health, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increasing burden of kidney failure (KF) in India necessitates provision of cost-effective kidney replacement therapy (KRT). We assessed the comparative cost-effectiveness of initiating KRT with peritoneal dialysis (PD) or haemodialysis (HD) in the Indian context.

methodsThe cost and clinical effectiveness of starting KRT with either PD or HD were measured in terms of life years (LYs) and quality-adjusted life years (QALYs) using a mathematical Markov model. Complications such as peritonitis, vascular access-related complications and blood-borne infections were considered. Health system costs, out-of-pocket expenditures borne by patients and indirect costs were included. Two scenarios were considered: Scenario 1 (real-world scenario)-as per the current cost and utilization patterns; Scenario 2 (public programme scenario)-use in the public sector as per Pradhan Mantri National Dialysis Programme (PMNDP) guidelines. The lifetime costs and health outcomes among KF patients were assessed.

resultsThe mean QALYs lived per KF person with PD and HD were estimated to be 3.3 and 1.6, respectively. From a societal perspective, a PD-first policy is cost-saving as compared with an HD-first policy in both Scenarios 1 and 2. If only the costs directly attributable to patient care (direct costs) are considered, the PD-first treatment policy is estimated to be cost-effective only if the price of PD consumables can be brought down to INR70/U.

conclusionsPD as initial treatment is a cost-saving option for management of KF in India as compared with HD first. The government should negotiate the price of PD consumables under the PMNDP.

Indexed as

chronic kidney diseasecontinuous ambulatory peritoneal dialysishaemodialysisperitoneal dialysis

Identifiers

PMID35035943
PMCPMC8757426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.