Evidence map›Paper›PMID 35035914›Full record

ArticleFood science & nutrition2022

Erucic acid exposure during the first year of life-Scenarios with precise food-based dietary guidelines.

Mathilde Kersting, Hermann Kalhoff, Bernd Honermeier, Kathrin Sinningen, Thomas Lücke

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mathilde KerstingResearch Department of Child Nutrition University Hospital of Pediatrics and Adolescent Medicine St. Josef-Hospital Ruhr-University Bochum Bochum Germany.ORCID https://orcid.org/0000-0001-6555-6104
Hermann KalhoffResearch Department of Child Nutrition University Hospital of Pediatrics and Adolescent Medicine St. Josef-Hospital Ruhr-University Bochum Bochum Germany.
Bernd HonermeierInstitute of Agronomy and Plant Breeding I Justus Liebig University Giessen Germany.
Kathrin SinningenResearch Department of Child Nutrition University Hospital of Pediatrics and Adolescent Medicine St. Josef-Hospital Ruhr-University Bochum Bochum Germany.
Thomas LückeResearch Department of Child Nutrition University Hospital of Pediatrics and Adolescent Medicine St. Josef-Hospital Ruhr-University Bochum Bochum Germany.
St. Josef-Hospital · DEJustus-Liebig-Universität Gießen · DEKlinikum Dortmund · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the European Food Safety Authority (EFSA) issued a tolerable daily intake (TDI) for erucic acid, which is mainly found in rapeseed oil. Infants may be exposed to erucic acid from rapeseed oil indirectly through maternal consumption via breastmilk or the fat component in formula, and directly as a part of complementary feeding (CF). To check the safety of infant nutrition, scenarios for erucic acid exposure were calculated based on the daily food amounts of the German dietary guidelines. Information on erucic acid concentrations in foods was obtained from European studies for breastmilk, from EFSA samples for formula powder, and from a representative analysis of rapeseed oil samples in the German retail market. 6 scenarios were calculated for the early milk feeding phase (4 formula feeding, 2 breastfeeding) and 8 scenarios for the later CF phase (5 CF +formula feeding, 3 CF +breastfeeding). Out of the 14 scenarios, only 3 resulted in exposures that were definitively below the TDI (range 4.4.-6.0 mg/kg bodyweight; BW). Assuming either high consumption or high concentration led to high exceedances (range 7.5-26.2 mg/kg BW), especially in case of the new EU limits for formula or vegetable oils (33.6 and 43.2 mg/kg BW, respectively). In our scenarios, high erucic acid exposures occurred during a particularly sensitive developmental period. To definitively weigh the potential risks from erucic acid in infants against nutritional benefits of the dietary recommendations, reliable, timely data on erucic acid in breast milk and formula are needed, similar to those from rapeseed oil in Germany.

Indexed as

exposure scenariosfood contaminantsinfant nutritionrapeseed oiltotal daily diet

Identifiers

PMID35035914
PMCPMC8751447
OpenAlexW3214455679

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.