Evidence map›Paper›PMID 35035905›Full record

ArticleFood science & nutrition2022

Hepatitis B virus genotype is an independent prognostic factor of telbivudine and tenofovir treatment in hepatitis B surface antigen-positive pregnant women.

Baofang Zhang, Lei Yu, Mingliang Cheng, Quan Zhang, Jun Wu, Jing Yang, Qin Liu, Shuang Lu, Xueke Zhao, KaiSheng Deng and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Baofang ZhangThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
Lei YuPrenatal Diagnosis Center Guizhou Medical University Guiyang, Guizhou China.
Mingliang ChengThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.ORCID https://orcid.org/0000-0001-7495-1106
Quan ZhangThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
Jun WuThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
Jing YangThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
Qin LiuThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
Shuang LuThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
Xueke ZhaoThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
KaiSheng DengThe Affliated Hospital Guizhou Medical University Guiyang, Guizhou China.
Yongmei LiuLaboratory Guizhou Medical University Guiyang, Guizhou China.
Jun WangClinical Research Center Guizhou Medical University Guiyang, Guizhou China.
Peiling ZhaoLaboratory Guizhou Medical University Guiyang, Guizhou China.
Guiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate whether HBV genotype influences the effect of tenofovir and telbivudine on HBV DNA and RNA levels in HBsAg-positive pregnant women. This was a retrospective study of 74 HBsAg-positive pregnant women in Guizhou of China. All patients were treated with telbivudine or tenofovir from 12 weeks of pregnancy and HBV infection to the date of delivery. Blood samples were collected at 12-24, 28-32, and 36-40 weeks of pregnancy for the measurement of genotype, HBsAg, hepatitis B e antigen (HBeAg), HBV DNA, HBV RNA, and liver function, including alanine transaminase, aspartate transaminase, total bilirubin, total bile acids, cholinesterase, alkaline phosphatase (ALP), and gamma-glutamyl transferase. All women with HBsAg were followed up. The HBV genotype was B in 64.9% and C in 35.1%. There were 37 patients of telbivudine and tenofovir group respectively. The telbivudine and tenofovir groups showed no differences in demographic and clinical characteristics, including liver function tests, HBsAg, HBeAg, log

Indexed as

genotypehepatitis B viruspregnancytelbivudinetenofovir

Identifiers

PMID35035905
PMCPMC8751444
OpenAlexW3215563428

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.