Evidence map›Paper›PMID 35035880›Full record

ArticleEpidemiology and psychiatric sciences2021

Association between physical-activity trajectories and cognitive decline in adults 50 years of age or older.

Boris Cheval, Zsófia Csajbók, Tomáš Formánek, Stefan Sieber, Matthieu P Boisgontier, Stéphane Cullati, Pavla Cermakova

Abstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Long-Term Exposure to Greenspace and Cognitive Function during the Lifespan: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Pooled it
  3. Article
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  7. Is the 10-Year Trajectory of Physical Activity Associated With the Incidence of Mild Cognitive Impairment in Older Adults?Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026
    Article
  8. Article
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  11. Nonlinear Associations of Accelerometer-Based Sedentary Time With Cognitive Functions in the UK Biobank.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
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  12. Article
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  17. Perceived Neighborhood Safety and Active Transportation in Adults from Eight Latin American Countries.International journal of environmental research and public health · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Boris ChevalSwiss Center for Affective Sciences, University of Geneva, Switzerland.
Zsófia CsajbókNational Institute of Mental Health, Klecany, Czech Republic.
Tomáš FormánekNational Institute of Mental Health, Klecany, Czech Republic.
Stefan SieberLIVES Centre, Swiss Centre of Expertise in Life Course Research, Switzerland.
Matthieu P BoisgontierSchool of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, Canada.
Stéphane CullatiPopulation Health Laboratory, University of Fribourg, Switzerland.
Pavla CermakovaNational Institute of Mental Health, Klecany, Czech Republic.

Funding

Medical Research Council MR/L017105/1NIA NIH HHS HHSN271201300071CSwiss National Science Foundation 180040
6 · The paper itself

Abstract

Aims: To investigate the associations of physical-activity trajectories with the level of cognitive performance and its decline in adults 50 years of age or older. Methods: We studied 38729 individuals (63 ± 9 years; 57% women) enrolled in the Survey of Health, Ageing and Retirement in Europe (SHARE). Physical activity was self-reported and cognitive performance was assessed based on immediate recall, verbal fluency, and delayed recall. Physical-activity trajectories were estimated using growth mixture modelling and linear mixed effects models were used to investigate the associations between the trajectories and cognitive performance. Results: The models identified two physical-activity trajectories of physical activity: constantly-high physical activity (N=27634: 71%) and decreasing physical activity (N=11095; 29%). Results showed that participants in the decreasing physical-activity group exhibited a lower level of cognitive performance compared to the high physical-activity group (immediate recall: ß=0.94; 95% confidence interval [CI]=0.92 to 0.95; verbal fluency: ß=0.98; 95% CI=0.97 to 0.98; delayed recall: ß=0.95; 95% CI=0.94 to 0.97). Moreover, compared with participants in the constantly-high physical-activity group, participants in the decreasing physical-activity group showed a steeper decline in all cognitive measures (immediate recall: ß=-0.04; 95% CI=-0.05 to -0.04; verbal fluency: ß=-0.22; 95% CI=-0.24 to -0.21; delayed recall: ß=-0.04; 95% CI=-0.05 to -0.04). Conclusions: Physical-activity trajectories are associated with the level and evolution of cognitive performance in adults over 50 years. Specifically, our findings suggest that a decline in physical activity over multiple years is associated with a lower level and a steeper decline in cognitive performance.

Indexed as

Cognitive DysfunctionAgingCognitionExerciseFemaleHealth SurveysHumansMaleMemory, Short-Term

Identifiers

PMID35035880
PMCPMC8728586

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.