Evidence map›Paper›PMID 35035782›Full record

ReviewJournal of oral microbiology2022

VBNC, previously unrecognized in the life cycle of

A Progulske-Fox, S S Chukkapalli, H Getachew, W A Dunn, J D Oliver

Open access · goldAbstract readReview
In one paragraph

Review in Journal of oral microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

A Progulske-FoxDepartment of Oral Biology, Center for Molecular Microbiology, University of Florida, Gainesville, FL, USA.
S S ChukkapalliDepartment of Oral Biology, Center for Molecular Microbiology, University of Florida, Gainesville, FL, USA.
H GetachewDepartment of Oral Biology, Center for Molecular Microbiology, University of Florida, Gainesville, FL, USA.
W A DunnDepartment of Anatomy and Cell Biology, University of Florida, Gainesville, FL, USA.
J D OliverDepartment of Biological Sciences, University of North Carolina, Charlotte, NC, USA.
University of Florida · USUniversity of North Carolina at Charlotte · US

Funding

Investigating the viable but not culturable (VBNC) state in P. gingivalisR01DE028656 · NIDCR · UNIVERSITY OF FLORIDA · PI PROGULSKE-FOX, ANN · 2020 to 2024
$1.8M
NIDCR NIH HHS R01 DE028656
6 · The paper itself

Abstract

Bacteria are exposed to stresses during their growth and multiplication in their ecological systems to which they respond in multiple ways as expert survivalists. One such response mechanism is to convert to a viable but not culturable (VBNC) state. As the name indicates, bacteria in the VBNC state have lost their ability to grow on routine growth medium. A large number of bacteria including many pathogenic species have been reported to be able to enter a VBNC state. VBNC differs from culturable cells in various physiological properties which may result in changes in chemical resistance, adhesion, cellular morphology, metabolism, gene expression, membrane and cell wall composition and/or virulence. The ability of VBNC bacteria to return to the culturable state or resuscitate, when the stressor is removed poses a considerable threat to public health. There have been few publications that overtly describe the ability of oral pathogenic species to enter the VBNC state. However, the presence of VBNCs among oral pathogens such as

Indexed as

chronic infectionsoral bacteriaP. gingivalisresuscitationVBNC

Identifiers

PMID35035782
PMCPMC8759725
OpenAlexW4205869267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.