Changes of inflammatory factors in patients after resection of lung adenocarcinoma with propofol and etomidate.

Xianjun Zheng, Lai Wei, Gaoyin Kong, Jinyu Jiang

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Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Xianjun ZhengDepartment of Anesthesiology, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University Changsha 410005, Hunan Province, China.

Lai WeiDepartment of Anesthesiology, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University Changsha 410005, Hunan Province, China.

Gaoyin KongDepartment of Anesthesiology, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University Changsha 410005, Hunan Province, China.

Jinyu JiangDepartment of Anesthesiology, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University Changsha 410005, Hunan Province, China.

Funding

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6 · The paper itself

Abstract

objectiveThis research was designed to investigate the changes of inflammatory factors in patients after resection of lung adenocarcinoma with propofol versus etomidate.

methodsA total of 104 patients who underwent resection of lung adenocarcinoma in our hospital were divided into a propofol group (group A, n=50) and an etomidate group (group B, n=54). The levels of CRP and IL-6 at different time points and the changes of blood gas indexes at 10 min before and after operation were observed in both groups. Their pain score and quality of life score were compared. Besides, we observed the wake-up time, tracheal extubation time and the incidence of adverse reactions.

resultsThe anesthesia recovery and tracheal extubation time in group B were shorter than those in group A (

conclusionEtomidate has better anesthetic effect than propofol in lung adenocarcinoma resection, leading to better stabilization of the vital signs of patients and it also has higher safety.

Indexed as

etomidateinflammatory factorsPropofolresection of lung adenocarcinoma

Identifiers

PMID35035751

PMCPMC8748119

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